Recombinant
RabMAb

Recombinant Anti-PSD95 antibody [EP2652Y] - BSA and Azide free (ab202495)

Overview

  • Product name

    Anti-PSD95 antibody [EP2652Y] - BSA and Azide free
    See all PSD95 primary antibodies
  • Description

    Rabbit monoclonal [EP2652Y] to PSD95 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC (PFA fixed), WB, IPmore details
    Unsuitable for: Flow Cyt,ICC/IF or IHC-P
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human PSD95 (N terminal). The exact sequence is proprietary.

  • General notes

    Ab202495 is the carrier-free version of ab76115. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab202495 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab202495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC (PFA fixed) Use at an assay dependent concentration. PubMed: 24991763
WB Use at an assay dependent concentration. Detects a band of approximately 95 kDa (predicted molecular weight: 95 kDa).
IP Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • Target

    • Function

      Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.
    • Tissue specificity

      Brain.
    • Sequence similarities

      Belongs to the MAGUK family.
      Contains 1 guanylate kinase-like domain.
      Contains 3 PDZ (DHR) domains.
      Contains 1 SH3 domain.
    • Domain

      The PDZ domain 3 mediates interaction with ADR1B.
      The L27 domain near the N-terminus of isoform 2 is required for HGS/HRS-dependent targeting to postsynaptic density.
    • Post-translational
      modifications

      Palmitoylation of isoform 1 is required for targeting to postsynaptic density.
    • Cellular localization

      Cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, axon. Cell junction, synapse. High levels in postsynaptic density of neurons in the forebrain. Also in presynaptic region of inhibitory synapses formed by cerebellar basket cells on axon hillocks of Purkinje cells.
    • Information by UniProt
    • Database links

    • Alternative names

      • Discs large homolog 4 antibody
      • Disks large homolog 4 antibody
      • DLG 4 antibody
      • Dlg4 antibody
      • DLG4_HUMAN antibody
      • FLJ97752 antibody
      • FLJ98574 antibody
      • Human post synaptic density protein 95 antibody
      • Post synaptic density protein 95 antibody
      • Postsynaptic density protein 95 antibody
      • PSD 95 antibody
      • PSD-95 antibody
      • PSD95 antibody
      • SAP 90 antibody
      • SAP-90 antibody
      • SAP90 antibody
      • Synapse associated protein 90 antibody
      • Synapse-associated protein 90 antibody
      • Tax interaction protein 15 antibody
      see all

    References

    ab202495 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab202495.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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