Anti-Pseudorabies Virus antibody (ab3534)
Key features and details
- Rabbit polyclonal to Pseudorabies Virus
- Suitable for: WB, IHC-Fr, ICC
- Isotype: IgG
Overview
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Product name
Anti-Pseudorabies Virus antibody -
Description
Rabbit polyclonal to Pseudorabies Virus -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Fr, ICCmore details -
Species reactivity
Reacts with: Other species -
Immunogen
Tissue, cells or virus corresponding to Pseudorabies Virus.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 99% PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab3534 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
Use a concentration of 0.2 - 1 µg/ml.
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| IHC-Fr |
Use a concentration of 1 µg/ml.
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| ICC |
Use at an assay dependent concentration.
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| Notes |
|---|
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WB
Use a concentration of 0.2 - 1 µg/ml. |
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IHC-Fr
Use a concentration of 1 µg/ml. |
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ICC
Use at an assay dependent concentration. |
Target
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Relevance
Pseudorabies virus (PRV) is a member of the neurotropic viruses known as alphaherpesviruses. PRV is primarily a disease of swine which serve as a reservoir for the virus and the principal source of natural infection for a diverse range of secondary hosts, including cattle, sheep, goats, dogs, cats, and many feral species. Humans and apes are refractory to PRV infection. PRV infects the epithelium of the host where it then spreads to axons of the peripheral nervous system (PNS). The virus opportunistically avails itself of the neuronal retrograde transport pathway which can facilitate transfer to the brain. This unique aspect of PRV allows it to be used as a powerful research tool to study neural connectivity and trace neuronal circuitry in the peripheral (PNS) and central nervous system (CNS). -
Database links
- SwissProt: P11871 Other species
- SwissProt: P50643 Other species
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Alternative names
- Alphaherpesvirus pseudorabies virus antibody
- PRV antibody
- Suid herpesvirus 1 antibody
- Suid herpesvirus type 1 antibody
Images
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Immunohistochemistry (Frozen sections) - Anti-Pseudorabies Virus antibody (ab3534)Immunohistochemical staining of PRV in rat hypothalamus from animals infected by injection of PRV into the vitreous body of the eye with ab3534.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab3534 has been referenced in 4 publications.
- Liu C et al. Genetic characterization and mutation analysis of Qihe547 Aujeszky's disease virus in China. BMC Vet Res 14:218 (2018). PubMed: 29980205
- Matthews DW et al. Feedback in the brainstem: an excitatory disynaptic pathway for control of whisking. J Comp Neurol 523:921-42 (2015). PubMed: 25503925
- Deshpande AJ et al. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell 26:896-908 (2014). PubMed: 25464900
- Asante CO et al. Cortical control of adaptive locomotion in wild-type mice and mutant mice lacking the ephrin-Eph effector protein alpha2-chimaerin. J Neurophysiol 104:3189-202 (2010). IHC-FoFr . PubMed: 20881205