Anti-PSG3 antibody (ab154700)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-PSG3 antibody
See all PSG3 primary antibodies -
DescriptionRabbit polyclonal to PSG3
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Host speciesRabbit
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Tested applicationsSuitable for: WB, IHC-Pmore details
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Species reactivityReacts with: Human
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Immunogen
Recombinant fragment corresponding to a region within amino acids 11 and 347 of Human PSG3 (Uniprot ID: Q16557)
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Positive control
- HCT116 whole cell lysate; Human colon cancer tissue.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol -
Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab154700 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 48 kDa. | |
| IHC-P | 1/100 - 1/1000. |
Target
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RelevanceThe human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain.
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Cellular localizationSecreted
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Database links
- Entrez Gene: 5671 Human
- Omim: 176392 Human
- SwissProt: Q16557 Human
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Alternative names
- carcinoembryonic antigen SG5 antibody
- pregnancy specific beta-1-glycoprotein 3 antibody
- Pregnancy specific glycoprotein 3 antibody
see all
Images
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Western blot - Anti-PSG3 antibody (ab154700)Anti-PSG3 antibody (ab154700) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg
Predicted band size: 48 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PSG3 antibody (ab154700)Immunohistochemical analysis of paraffin-embedded colon cancer tissue, labeling PSG3 using ab154700 at 1/500 dilution.
References
ab154700 has not yet been referenced specifically in any publications.
