Key features and details
- Rabbit polyclonal to PSMD11 (HRP)
- Suitable for: WB
- Reacts with: Mouse, Rat, Dog, Human, Zebrafish
- Conjugation: HRP
- Isotype: IgG
Product nameAnti-PSMD11 antibody (HRP)
See all PSMD11 primary antibodies
DescriptionRabbit polyclonal to PSMD11 (HRP)
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Dog, Human, Zebrafish
Predicted to work with: Cow
Recombinant full length protein corresponding to Human PSMD11 aa 2-422.
AAAAVVEFQRAQSLLSTDREASIDILHSIVKRDIQENDEEAVQVKEQSIL ELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEA ATGQEVELCLECIEWAKSEKRTFLRQALEARLVSLYFDTKRYQEALHLGS QLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIY CPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSL KYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNRSLAD FEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHIS SLIKLSKADVERKLSQMILDKKFHGILDQGEGVLIIFDEPPVDKTYEAAL ETIQNMSKVVDSLYNKAKKLT
Database link: O00231
- EC109 whole cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.40
Constituents: 50% Glycerol, 49% PBS, 0.03% Proclin 300
Concentration information loading...
PurityCaprylic Acid - Ammonium Sulfate precipitation
Our Abpromise guarantee covers the use of ab193139 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/20 - 1/300. Predicted molecular weight: 47 kDa.|
FunctionComponent of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs): its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Tissue specificityHighly expressed in embryonic stem cells (ESCs). Expression decreases as ESCs differentiate.
Sequence similaritiesBelongs to the proteasome subunit S9 family.
Contains 1 PCI domain.
modificationsPhosphorylated by AMPK.
Cellular localizationNucleus. Cytoplasm > cytosol.
- Information by UniProt
- 26S proteasome non-ATPase regulatory subunit 11 antibody
- 26S proteasome regulatory subunit 9 antibody
- 26S proteasome regulatory subunit p44.5 antibody
ab193139 has not yet been referenced specifically in any publications.