Overview

  • Product name
  • Description
    Rabbit polyclonal to PSPH
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PSPH aa 7-36 (N terminal) conjugated to keyhole limpet haemocyanin.
    Database link: NP_004568.2

  • Positive control
    • Mouse NIH-3T3 cell line lysates.
  • General notes

    Previously labelled as Phosphoserine phosphatase.

Properties

Applications

Our Abpromise guarantee covers the use of ab156414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 25 kDa.

Target

  • Function
    Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates.
  • Pathway
    Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.
  • Involvement in disease
    Defects in PSPH are the cause of phosphoserine phosphatase deficiency (PSPHD)[MIM:614023]. A disorder that results in pre- and postnatal growth retardation, moderate psychomotor retardation and facial features suggestive of Williams syndrome.
  • Sequence similarities
    Belongs to the SerB family.
  • Information by UniProt
  • Database links
  • Alternative names
    • EC 3.1.3.3 antibody
    • L 3 phosphoserine phosphatase antibody
    • L-3-phosphoserine phosphatase antibody
    • O phosphoserine phosphohydrolase antibody
    • O-phosphoserine phosphohydrolase antibody
    • Phosphoserine phosphatase antibody
    • Phosphoserine phosphatase deficiency, included antibody
    • PSP antibody
    • PSPase antibody
    • Psph antibody
    • PSPHD antibody
    • SERB_HUMAN antibody
    see all

Images

  • Anti-PSPH antibody (ab156414) at 1/100 dilution + Mouse NIH-3T3 cell line lysates at 35 µg

    Predicted band size: 25 kDa

References

This product has been referenced in:
  • Yamanishi A  et al. Collection of homozygous mutant mouse embryonic stem cells arising from autodiploidization during haploid gene trap mutagenesis. Nucleic Acids Res 46:e63 (2018). Read more (PubMed: 29554276) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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