Overview

  • Product name

  • Description

    Rabbit polyclonal to PTDSS1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human PTDSS1 aa 1-35.
    Database link: P48651

  • Positive control

    • WB: EC109 and HEK-293T whole cell lysates. IHC-P: Human liver tissue. ICC/IF: HepG2 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.03% Proclin
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purity >95%.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab237019 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 56, 39, 35 kDa.
IHC-P 1/20 - 1/200.
ICC/IF 1/50 - 1/200.

Target

  • Relevance

    Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium dependent base exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).
  • Cellular localization

    Membrane; Multi pass membrane protein.
  • Database links

  • Alternative names

    • Phosphatidylserine synthase 1 antibody
    • PSS1 antibody
    • PSSA antibody
    • PtdSer synthase 1 antibody
    • Serine exchange enzyme I antibody
    see all

Images

  • All lanes : Anti-PTDSS1 antibody (ab237019) at 1/500 dilution

    Lane 1 : EC109 whole cell lysate
    Lane 2 : HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate

    Secondary
    All lanes : Goat polyclonal to Rabbit IgG at 1/50000 dilution

    Predicted band size: 56, 39, 35 kDa

  • Paraffin-embedded human liver tissue stained for PTDSS1 using ab237019 at 1/100 dilution in immunohistochemical analysis.

  • HepG2 (Human liver hepatocellular carcinoma cell line) cells stained for PTDSS1 (green) using ab237019 at 1/100 dilution in ICC/IF, followed by an Alexa-Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

References

ab237019 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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