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ab32199 has been referenced in 73 publications.

  • Zakharia K  et al. Preclinical In Vitro and In Vivo Evidence of an Antitumor Effect of CX-4945, a Casein Kinase II Inhibitor, in Cholangiocarcinoma. Transl Oncol 12:143-153 (2019). PubMed: 30316146
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  • Liu L  et al. PTEN inhibits non-small cell lung cancer cell growth by promoting G0/G1 arrest and cell apoptosis. Oncol Lett 17:1333-1340 (2019). PubMed: 30655903
  • Xing Y & Li L Gastrodin protects rat cardiomyocytes H9c2 from hypoxia-induced injury by up-regulation of microRNA-21. Int J Biochem Cell Biol 109:8-16 (2019). PubMed: 30684569
  • Egiz M  et al. La-Related Protein 4 as a Suppressor for Motility of Ovarian Cancer Cells. Tohoku J Exp Med 247:59-67 (2019). PubMed: 30686809
  • Bai J  et al. lncRNA A1BG-AS1 suppresses proliferation and invasion of hepatocellular carcinoma cells by targeting miR-216a-5p. J Cell Biochem N/A:N/A (2018). PubMed: 30556161
  • Ma X  et al. LncRNA ANCR promotes proliferation and radiation resistance of nasopharyngeal carcinoma by inhibiting PTEN expression. Onco Targets Ther 11:8399-8408 (2018). PubMed: 30568463
  • Yin L  et al. Analysis of PTEN expression and promoter methylation in Uyghur patients with mild type 2 diabetes mellitus. Medicine (Baltimore) 97:e13513 (2018). PubMed: 30544451
  • Cai B  et al. ß-elemene induced anticancer effect in bladder cancer through upregulation of PTEN and suppression of AKT phosphorylation. Oncol Lett 16:6019-6025 (2018). PubMed: 30333873
  • Li BH  et al. Up-Regulation of Phosphatase in Regenerating Liver-3 (PRL-3) Contributes to Malignant Progression of Hepatocellular Carcinoma by Activating Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN)/Phosphoinositide 3-Kinase (PI3K)/AKT Signaling Pathway. Med Sci Monit 24:8105-8114 (2018). PubMed: 30418964
  • Li T  et al. Formononetin induces vasorelaxation in rat thoracic aorta via regulation of the PI3K/PTEN/Akt signaling pathway. Drug Des Devel Ther 12:3675-3684 (2018). PubMed: 30464399
  • Fan D  et al. MicroRNA 26b promotes colorectal cancer metastasis by downregulating phosphatase and tensin homolog and wingless-type MMTV integration site family member 5A. Cancer Sci 109:354-362 (2018). WB ; Human . PubMed: 29160937
  • Yang N  et al. Epigallocatechin-3-gallate inhibits inflammation and epithelial-mesenchymal transition through the PI3K/AKT pathway via upregulation of PTEN in asthma. Int J Mol Med 41:818-828 (2018). WB ; Mouse . PubMed: 29207033
  • Yan F  et al. Role of miR-21 in the growth and metastasis of human salivary adenoid cystic carcinoma. Mol Med Rep 17:4237-4244 (2018). PubMed: 29328455
  • Choi WH  et al. Microsatellite Alterations and Protein Expression of 5 Major Tumor Suppressor Genes in Gastric Adenocarcinomas. Transl Oncol 11:43-55 (2018). IHC-P ; Human . PubMed: 29172180
  • Chu P  et al. miR-205 regulates the proliferation and invasion of ovarian cancer cells via suppressing PTEN/SMAD4 expression. Oncol Lett 15:7571-7578 (2018). PubMed: 29725462
  • Zhu HY  et al. Long non-coding RNA UCA1 desensitizes breast cancer cells to trastuzumab by impeding miR-18a repression of Yes-associated protein 1. Biochem Biophys Res Commun 496:1308-1313 (2018). WB . PubMed: 29408336
  • Sepe R  et al. The Long Non-Coding RNA RP5-1024C24.1 and Its Associated-Gene MPPED2 Are Down-Regulated in Human Thyroid Neoplasias and Act as Tumour Suppressors. Cancers (Basel) 10:N/A (2018). PubMed: 29783666
  • Yarushkin AA  et al. CAR-mediated repression of Cdkn1a(p21) is accompanied by the Akt activation. Biochem Biophys Res Commun N/A:N/A (2018). WB . PubMed: 29890134
  • Han W & Liu J LncRNA-p21 inhibited the proliferation of osteosarcoma cells via the miR-130b/PTEN/AKT signaling pathway. Biomed Pharmacother 97:911-918 (2018). WB . PubMed: 29136769
  • Tan Z  et al. MiR-150-3p targets SP1 and suppresses the growth of glioma cells. Biosci Rep 38:N/A (2018). PubMed: 29654167
  • Sang Q  et al. CircSNCA downregulation by pramipexole treatment mediates cell apoptosis and autophagy in Parkinson's disease by targeting miR-7. Aging (Albany NY) 10:1281-1293 (2018). PubMed: 29953413
  • Huang R  et al. EPS8 regulates proliferation, apoptosis and chemosensitivity in BCR-ABL positive cells via the BCR-ABL/PI3K/AKT/mTOR pathway. Oncol Rep 39:119-128 (2018). PubMed: 29192326
  • Lu C  et al. Baicalein inhibits cell growth and increases cisplatin sensitivity of A549 and H460 cells via miR-424-3p and targeting PTEN/PI3K/Akt pathway. J Cell Mol Med N/A:N/A (2018). PubMed: 29392841
  • Yan B  et al. Long non-coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3-kinase/protein kinase B signaling pathway. Exp Ther Med 15:4829-4837 (2018). PubMed: 29805503
  • Li M  et al. Loss of selenocysteine insertion sequence binding protein 2 suppresses the proliferation, migration/invasion and hormone secretion of human trophoblast cells via the PI3K/Akt and ERK signaling pathway. Placenta 55:81-89 (2017). PubMed: 28623977
  • Sui J  et al. Long Non-Coding RNA Linc-USP16 Functions As a Tumour Suppressor in Hepatocellular Carcinoma by Regulating PTEN Expression. Cell Physiol Biochem 44:1188-1198 (2017). PubMed: 29179215
  • Xie Y  et al. Anti-diabetic effect of Alpinia oxyphylla extract on 57BL/KsJ db-/db- mice. Exp Ther Med 13:1321-1328 (2017). WB ; Mouse . PubMed: 28413472
  • Weng M  et al. The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer. Oncotarget 8:20288-20296 (2017). WB ; Human . PubMed: 28423617
  • Gong Y  et al. Elucidating the mechanism of miRNA-214 in the regulation of gingival carcinoma. Exp Ther Med 13:2544-2550 (2017). PubMed: 28565877
  • Hu J  et al. Tumor grade related expression of neuroglobin is negatively regulated by PPAR? and confers antioxidant activity in glioma progression. Redox Biol 12:682-689 (2017). WB . PubMed: 28410531
  • Yu X  et al. miRNA-21 enhances chemoresistance to cisplatin in epithelial ovarian cancer by negatively regulating PTEN. Oncol Lett 14:1807-1810 (2017). PubMed: 28789414
  • Wang L  et al. Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells through the PI3K/Akt/FoxO1 pathway. Sci Rep 7:5384 (2017). PubMed: 28710412
  • Guo J  et al. miR-20b promotes cellular proliferation and migration by directly regulating phosphatase and tensin homolog in prostate cancer. Oncol Lett 14:6895-6900 (2017). PubMed: 29163708
  • Shi ZX  et al. Yi-qi-yang-yin-tang increases the sensitivity of KG1a leukemia stem cells to daunorubicin by promoting cell cycle progression and regulating the expression of PTEN, TOPOII and mTOR. Oncol Lett 14:6441-6448 (2017). PubMed: 29163680
  • Dong P  et al. Musashi-2, a novel oncoprotein promoting cervical cancer cell growth and invasion, is negatively regulated by p53-induced miR-143 and miR-107 activation. J Exp Clin Cancer Res 36:150 (2017). PubMed: 29073938
  • Na YS  et al. Establishment and characterization of patient-derived xenograft models of gastrointestinal stromal tumor resistant to standard tyrosine kinase inhibitors. Oncotarget 8:76712-76721 (2017). PubMed: 29100343
  • Qian LQ  et al. Downregulation of MACC1 inhibits the viability, invasion and migration and induces apoptosis in esophageal carcinoma cells through the phosphatase and tensin homolog/phosphoinositide 3-kinase/protein kinase B signaling pathway. Oncol Lett 14:4897-4905 (2017). PubMed: 29085498
  • Javadi A  et al. PTEN controls glandular morphogenesis through a juxtamembrane ß-Arrestin1/ARHGAP21 scaffolding complex. Elife 6:N/A (2017). PubMed: 28749339
  • Huang ZJ  et al. NEDD4 promotes cell growth and migration via PTEN/PI3K/AKT signaling in hepatocellular carcinoma. Oncol Lett 14:2649-2656 (2017). PubMed: 28928809
  • Shao P  et al. MicroRNA-205-5p regulates the chemotherapeutic resistance of hepatocellular carcinoma cells by targeting PTEN/JNK/ANXA3 pathway. Am J Transl Res 9:4300-4307 (2017). PubMed: 28979703
  • Hu G  et al. Single-cell RNA-seq reveals distinct injury responses in different types of DRG sensory neurons. Sci Rep 6:31851 (2016). IHC . PubMed: 27558660
  • Ma J  et al. microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injury. Am J Transl Res 8:1895-902 (2016). WB ; Rat . PubMed: 27186313
  • Chang H  et al. EGFR protein expression using a specific intracellular domain antibody and PTEN and clinical outcomes in squamous cell lung cancer patients with EGFR-tyrosine kinase inhibitor therapy. Onco Targets Ther 9:5153-62 (2016). IHC ; Human . PubMed: 27578983
  • Gusscott S  et al. IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias. PLoS One 11:e0161158 (2016). WB . PubMed: 27532210
  • He S  et al. Upregulation of PREX2 promotes the proliferation and migration of hepatocellular carcinoma cells via PTEN-AKT signaling. Oncol Lett 11:2223-2228 (2016). Human . PubMed: 26998152
  • Yang J  et al. PREX2 promotes the proliferation, invasion and migration of pancreatic cancer cells by modulating the PI3K signaling pathway. Oncol Lett 12:1139-1143 (2016). WB ; Human . PubMed: 27446408
  • Bei Y  et al. miR-382 targeting PTEN-Akt axis promotes liver regeneration. Oncotarget 7:1584-97 (2016). WB . PubMed: 26636539
  • Ma Q  et al. miR-19a correlates with poor prognosis of clear cell renal cell carcinoma patients via promoting cell proliferation and suppressing PTEN/SMAD4 expression. Int J Oncol 49:2589-2599 (2016). PubMed: 27779660
  • Fan Y  et al. Cytotoxic effects of ß-carboline alkaloids on human gastric cancer SGC-7901 cells. Int J Clin Exp Med 8:12977-82 (2015). PubMed: 26550217
  • Serra H  et al. PTEN mediates Notch-dependent stalk cell arrest in angiogenesis. Nat Commun 6:7935 (2015). PubMed: 26228240
  • Liu CJ  et al. MiR-214 promotes osteosarcoma tumor growth and metastasis by decreasing the expression of PTEN. Mol Med Rep 12:6261-6 (2015). PubMed: 26252022
  • Geng J  et al. Down-regulation of USP13 mediates phenotype transformation of fibroblasts in idiopathic pulmonary fibrosis. Respir Res 16:124 (2015). WB . PubMed: 26453058
  • He M  et al. KLF4 mediates the link between TGF-ß1-induced gene transcription and H3 acetylation in vascular smooth muscle cells. FASEB J 29:4059-70 (2015). PubMed: 26082460
  • Li CJ  et al. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest 125:1509-22 (2015). WB ; Mouse . PubMed: 25751060
  • Sellerio AL  et al. Overshoot during phenotypic switching of cancer cell populations. Sci Rep 5:15464 (2015). PubMed: 26494317
  • Liao HF  et al. DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells. Development 141:2402-13 (2014). PubMed: 24850856
  • Ngalame NN  et al. Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic. Toxicol Sci 138:268-77 (2014). PubMed: 24431212
  • Screen M  et al. Abnormal splicing of NEDD4 in myotonic dystrophy type 2: possible link to statin adverse reactions. Am J Pathol 184:2322-32 (2014). PubMed: 24907641
  • Hammond VE  et al. Ndfip1 Is Required for the Development of Pyramidal Neuron Dendrites and Spines in the Neocortex. Cereb Cortex N/A:N/A (2013). PubMed: 23897647
  • Surviladze Z  et al. Cellular entry of human papillomavirus type 16 involves activation of the phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy. J Virol 87:2508-17 (2013). PubMed: 23255786
  • Kucherlapati MH  et al. Genotype directed therapy in murine mismatch repair deficient tumors. PLoS One 8:e68817 (2013). PubMed: 23935891
  • Xu Y  et al. Recruitment of normal stem cells to an oncogenic phenotype by noncontiguous carcinogen-transformed epithelia depends on the transforming carcinogen. Environ Health Perspect 121:944-50 (2013). WB ; Human . PubMed: 23687063
  • Howitt J  et al. Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. J Cell Biol 196:29-36 (2012). PubMed: 22213801
  • Sangale Z  et al. A robust immunohistochemical assay for detecting PTEN expression in human tumors. Appl Immunohistochem Mol Morphol 19:173-83 (2011). PubMed: 20930614
  • Manna P & Jain SK Hydrogen Sulfide and L-Cysteine Increase Phosphatidylinositol 3,4,5-Trisphosphate (PIP3) and Glucose Utilization by Inhibiting Phosphatase and Tensin Homolog (PTEN) Protein and Activating Phosphoinositide 3-Kinase (PI3K)/Serine/Threonine Protein Kinase (AKT)/Protein Kinase C?/? (PKC?/?) in 3T3l1 Adipocytes. J Biol Chem 286:39848-59 (2011). WB ; Mouse . PubMed: 21953448
  • Medyouf H  et al. Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss. Blood 115:1175-84 (2010). Flow Cyt ; Human . PubMed: 20008304
  • Akesson E  et al. Prognostic significance of estrogen and progesterone receptor expression in LNG-IUS (Mirena) treatment of endometrial hyperplasia: an immunohistochemical study. Acta Obstet Gynecol Scand 89:393-8 (2010). IHC-P ; Human . PubMed: 20199355
  • Wargon V  et al. Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas. Breast Cancer Res Treat : (2010). WB ; Mouse . PubMed: 20440553
  • Vlashi E  et al. Differential Effects of the Proteasome Inhibitor NPI-0052 against Glioma Cells. Transl Oncol 3:50-5 (2010). WB ; Human . PubMed: 20165695
  • Lee DY  et al. Expression of Versican 3'-Untranslated Region Modulates Endogenous MicroRNA Functions. PLoS One 5:e13599 (2010). WB, IHC-P ; Mouse . PubMed: 21049042
  • Diegel CR  et al. Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of apc and pten in the mouse salivary gland: implications for human acinic cell carcinoma. Cancer Res 70:9143-52 (2010). IHC-P ; Mouse . PubMed: 21062985
  • Zeiser R  et al. Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells. Blood 111:453-62 (2008). PubMed: 17967941

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