• Product name

  • Description

    Rabbit polyclonal to PTGES2/Gbf1
  • Host species

  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Cow, Cynomolgus monkey
  • Immunogen

    Recombinant fragment corresponding to Human PTGES2/Gbf1 aa 82-160.
    Database link: Q9H7Z7

  • Positive control

    • RT4 cell line lysate.; Human heart muscle tissue.
  • General notes

     This product was previously labelled as PTGES2




Our Abpromise guarantee covers the use of ab220013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/250. Predicted molecular weight: 42 kDa.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.

Antigen retrieval buffer pH6


  • Function

    Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear.
  • Tissue specificity

    Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes. Also expressed in the lymph nodes, skeletal muscle, kidney and trachea, but not in the thymus or lung. Overexpressed in colorectal cancer.
  • Pathway

    Lipid metabolism; prostaglandin biosynthesis.
  • Sequence similarities

    Belongs to the GST superfamily.
    Contains 1 glutaredoxin domain.
    Contains 1 GST C-terminal domain.
  • Cellular localization

    Golgi apparatus membrane and Cytoplasm > perinuclear region. Synthetized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. The truncated form is cytoplasmic and is enriched in the perinuclear region.
  • Information by UniProt
  • Database links

  • Alternative names

    • C9orf15 antibody
    • FLJ14038 antibody
    • Gamma interferon activated transcriptional element binding factor 1 antibody
    • GATE binding factor 1 antibody
    • GBF 1 antibody
    • GBF1 antibody
    • Membrane associated prostaglandin E synthase 2 antibody
    • MGC11289 antibody
    • Microsomal prostaglandin E synthase 2 antibody
    • mPGES 2 antibody
    • mPGES-2 antibody
    • PGES2 antibody
    • PGES2_HUMAN antibody
    • Prostaglandin E synthase 2 antibody
    • Prostaglandin E synthase 2 truncated form antibody
    • PTGES 2 antibody
    • PTGES2 antibody
    see all


  • Immunohistochemical analysis of formailin fixed, paraffin embedded Human heart muscle tissue labeling PTGES2/Gbf1 with ab220013 at 1/50 dilution.

  • Anti-PTGES2/Gbf1 antibody (ab220013) at 1/100 dilution + RT4 cell line lysate

    Predicted band size: 42 kDa


ab220013 has not yet been referenced specifically in any publications.

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