Key features and details
- Rabbit polyclonal to PTGES2/Gbf1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-PTGES2/Gbf1 antibody
See all PTGES2/Gbf1 primary antibodies
DescriptionRabbit polyclonal to PTGES2/Gbf1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow, Dog
Recombinant fragment corresponding to Human PTGES2/Gbf1 aa 106-313.
Database link: NP_079348
- 293T and Molt4 whole cell lysates; HepG2 and Raji lysates
This product was previously labelled as PTGES2
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab96189 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 42 kDa.|
FunctionIsomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear.
Tissue specificityWidely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes. Also expressed in the lymph nodes, skeletal muscle, kidney and trachea, but not in the thymus or lung. Overexpressed in colorectal cancer.
PathwayLipid metabolism; prostaglandin biosynthesis.
Sequence similaritiesBelongs to the GST superfamily.
Contains 1 glutaredoxin domain.
Contains 1 GST C-terminal domain.
Cellular localizationGolgi apparatus membrane and Cytoplasm > perinuclear region. Synthetized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. The truncated form is cytoplasmic and is enriched in the perinuclear region.
- Information by UniProt
- C9orf15 antibody
- FLJ14038 antibody
- Gamma interferon activated transcriptional element binding factor 1 antibody
ab96189 has been referenced in 2 publications.
- Xi J et al. Celastrol inhibits glucocorticoid-induced osteoporosis in rat via the PI3K/AKT and Wnt signaling pathways. Mol Med Rep 18:4753-4759 (2018). PubMed: 30221712
- Samavedi S et al. A Three-Dimensional Chondrocyte-Macrophage Coculture System to Probe Inflammation in Experimental Osteoarthritis. Tissue Eng Part A 23:101-114 (2017). PubMed: 27736317