Anti-PTGFRN antibody (ab97567)
Key features and details
- Rabbit polyclonal to PTGFRN
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-PTGFRN antibody
See all PTGFRN primary antibodies -
Description
Rabbit polyclonal to PTGFRN -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to a region within amino acids 815 - 879 (KPVFITVKMD VLNAFKYPLL IGVGLSTVIG LLSCLIGYCS SHWCCKKEVQ ETRRERRRLM SMEMD) of Human PTGFRN (NP_065173).
-
Positive control
- H1299, 293T or A431 cell lysate.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab97567 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 99 kDa.
|
Notes |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 99 kDa. |
Target
-
Function
Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur. -
Sequence similarities
Contains 6 Ig-like C2-type (immunoglobulin-like) domains. -
Cellular localization
Endoplasmic reticulum membrane. Golgi apparatus > trans-Golgi network membrane. - Information by UniProt
-
Database links
- Entrez Gene: 5738 Human
- Entrez Gene: 19221 Mouse
- Entrez Gene: 29602 Rat
- Omim: 601204 Human
- SwissProt: Q9P2B2 Human
- SwissProt: Q9WV91 Mouse
- SwissProt: Q62786 Rat
- Unigene: 418093 Human
see all -
Alternative names
- CD315 antibody
- CD9 partner 1 antibody
- CD9P-1 antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (3)
ab97567 has been referenced in 3 publications.
- Mala U et al. Integrative analysis of cell adhesion molecules in glioblastoma identified prostaglandin F2 receptor inhibitor (PTGFRN) as an essential gene. BMC Cancer 22:642 (2022). PubMed: 35690717
- Yi H et al. Knockdown of long non-coding RNA DLEU2 suppresses idiopathic pulmonary fibrosis by regulating the microRNA-369-3p/TRIM2 axis. Int J Mol Med 47:N/A (2021). PubMed: 33760118
- Aguila B et al. The Ig superfamily protein PTGFRN coordinates survival signaling in glioblastoma multiforme. Cancer Lett 462:33-42 (2019). PubMed: 31377205