Overview

  • Product name

  • Description

    Goat polyclonal to PTGIS/PGIS
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PTGIS/PGIS aa 248-258 (internal sequence) (Cysteine residue). (NP_000952.1).
    Sequence:

    C-RRAHRSKWLES


    Database link: Q16647

  • Positive control

    • WB: Human lung and ovary lysates.
  • General notes

     This product was previously labelled as PTGIS

     

Properties

Applications

Our Abpromise guarantee covers the use of ab223578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 57 kDa).

Target

  • Function

    Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
  • Tissue specificity

    Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CYP8 antibody
    • CYP8A1 antibody
    • Cytochrome P450, family 8, subfamily A, polypeptide 1 antibody
    • EC 5.3.99.4 antibody
    • MGC126858 antibody
    • MGC126860 antibody
    • OTTHUMP00000031777 antibody
    • PGIS antibody
    • Prostacyclin synthase antibody
    • Prostaglandin I2 (prostacyclin) synthase antibody
    • Prostaglandin I2 synthase antibody
    • PTGI antibody
    • PTGIS antibody
    • PTGIS_HUMAN antibody
    see all

Images

  • All lanes : Anti-PTGIS/PGIS antibody (ab223578) at 0.5 µg/ml

    Lane 1 : Human lung lysate (in RIPA buffer)
    Lane 2 : Human ovary lysate (in RIPA buffer)

    Lysates/proteins at 35 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 57 kDa
    Observed band size: 55 kDa
    why is the actual band size different from the predicted?



    Primary incubation was 1 hour.

References

ab223578 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab223578.
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