Anti-PTGR1 antibody (ab229567)
Key features and details
- Rabbit polyclonal to PTGR1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-PTGR1 antibody
See all PTGR1 primary antibodies -
Description
Rabbit polyclonal to PTGR1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment within Human PTGR1 (internal sequence). The exact sequence is proprietary.
Database link: Q14914 -
Positive control
- WB: PL45, PANC-1, MIAPACA2, BxPC-3 and Capan2 whole cell lysates.
-
General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
-
Related Products
Applications
Our Abpromise guarantee covers the use of ab229567 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 35 kDa. |
Target
-
Function
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4. -
Tissue specificity
High expression in the kidney, liver, and intestine but not in leukocytes. -
Sequence similarities
Belongs to the NADP-dependent oxidoreductase L4BD family. -
Cellular localization
Cytoplasm. - Information by UniProt
-
Database links
- Entrez Gene: 22949 Human
- Omim: 601274 Human
- SwissProt: Q14914 Human
- Unigene: 584864 Human
-
Alternative names
- 15-oxoprostaglandin 13-reductase antibody
- FLJ99229 antibody
- leukotriene B4 12-hydroxydehydrogenase antibody
see all
Images
-
Western blot - Anti-PTGR1 antibody (ab229567)All lanes : Anti-PTGR1 antibody (ab229567) at 1/500 dilution
Lane 1 : PL45 whole cell lysate
Lane 2 : PANC-1 (human pancreatic epithelial carcinoma cell line) whole cell lysate
Lane 3 : MIAPACA2 whole cell lysate
Lane 4 : BxPC-3 (human pancreas adenocarcinoma cell line) whole cell lysate
Lane 5 : Capan2 whole cell lysate
Lysates/proteins at 40 µg per lane.
Predicted band size: 35 kDa
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab229567 has not yet been referenced specifically in any publications.
