Anti-PTGR1 antibody (ab229567)

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Overview

  • Product name

    Anti-PTGR1 antibody
    See all PTGR1 primary antibodies

  • Description

    Rabbit polyclonal to PTGR1

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant fragment within Human PTGR1 (internal sequence). The exact sequence is proprietary.
    Database link: Q14914

  • Positive control

    • WB: PL45, PANC-1, MIAPACA2, BxPC-3 and Capan2 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab229567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 35 kDa.

Target

  • Function

    Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-oxo-PGE1, 15-oxo-PGE2 and 15-oxo-PGE2-alpha. Has no activity towards PGE1, PGE2 and PGE2-alpha (By similarity). Catalyzes the conversion of leukotriene B4 into its biologically less active metabolite, 12-oxo-leukotriene B4. This is an initial and key step of metabolic inactivation of leukotriene B4.

  • Tissue specificity

    High expression in the kidney, liver, and intestine but not in leukocytes.

  • Sequence similarities

    Belongs to the NADP-dependent oxidoreductase L4BD family.

  • Cellular localization

    Cytoplasm.
  • Information by UniProt

  • Database links

    • Alternative names

      • 15-oxoprostaglandin 13-reductase antibody
      • FLJ99229 antibody
      • leukotriene B4 12-hydroxydehydrogenase antibody
      • LTB4DH antibody
      • MGC34943 antibody
      • NADP-dependent leukotriene B4 12-hydroxydehydrogenase antibody
      • PGR1 antibody
      • PRG-1 antibody
      • Prostaglandin reductase 1 antibody
      • Ptgr1 antibody
      • PTGR1_HUMAN antibody
      • RP11-16L21.1 antibody
      • ZADH3 antibody
      • zinc binding alcohol dehydrogenase domain containing 3 antibody
      see all

    Images

    • Western blot - Anti-PTGR1 antibody (ab229567)
      Western blot - Anti-PTGR1 antibody (ab229567)
      All lanes : Anti-PTGR1 antibody (ab229567) at 1/500 dilution

      Lane 1 : PL45 whole cell lysate
      Lane 2 : PANC-1 (human pancreatic epithelial carcinoma cell line) whole cell lysate
      Lane 3 : MIAPACA2 whole cell lysate
      Lane 4 : BxPC-3 (human pancreas adenocarcinoma cell line) whole cell lysate
      Lane 5 : Capan2 whole cell lysate

      Lysates/proteins at 40 µg per lane.

      Predicted band size: 35 kDa

    References

    ab229567 has not yet been referenced specifically in any publications.

    Publishing research using ab229567? Please let us know so that we can cite the reference in this datasheet.

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