Overview

  • Product name

  • Description

    Rabbit polyclonal to PTGR2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to Human PTGR2 aa 108-157 (internal sequence).
    Database link: NP_689657

  • Positive control

    • MCF7 cell lysate
  • General notes

     This product was previously labelled as ZADH1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab84711 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 38 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function

    Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
  • Tissue specificity

    Widely expressed.
  • Sequence similarities

    Belongs to the NADP-dependent oxidoreductase L4BD family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • 15 oxoprostaglandin 13 reductase antibody
    • 15 oxoprostaglandin delta 13 reductase antibody
    • 15-oxoprostaglandin 13-reductase antibody
    • DKFZp686P10120 antibody
    • FLJ39091 antibody
    • FLJ99229 antibody
    • PGR 2 antibody
    • PGR2 antibody
    • PRG-2 antibody
    • Prostaglandin reductase 2 antibody
    • PTGR 2 antibody
    • PTGR2 antibody
    • PTGR2_HUMAN antibody
    • Zinc binding alcohol dehydrogenase domain containing 1 antibody
    • Zinc binding alcohol dehydrogenase domain containing protein 1 antibody
    • Zinc-binding alcohol dehydrogenase domain-containing protein 1 antibody
    see all

Images

  • Anti-PTGR2 antibody (ab84711) at 1 µg/ml (in 5% skim milk / PBS buffer) + MCF7 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size: 38 kDa
    Observed band size: 38 kDa
    Additional bands at: 55 kDa. We are unsure as to the identity of these extra bands.

References

This product has been referenced in:

  • Gedik N  et al. Proteomics/phosphoproteomics of left ventricular biopsies from patients with surgical coronary revascularization and pigs with coronary occlusion/reperfusion: remote ischemic preconditioning. Sci Rep 7:7629 (2017). Read more (PubMed: 28794502) »
See 1 Publication for this product

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