Overview

  • Product name

    Anti-PTPLB antibody
  • Description

    Rabbit polyclonal to PTPLB
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human PTPLB aa 7-41.
    Sequence:

    TAAAKGNGGGGGRAGAGDASGTRKKKGPGPLATAY


    Database link: Q6Y1H2

  • Positive control

    • WB: MCF7 and LO2 whole cell lysate. IHC-P: Human prostate cancer tissue. ICC/IF: MCF7 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab237046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.
WB 1/500 - 1/2000.
ICC/IF 1/50 - 1/200.

Target

  • Function

    Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis.
  • Tissue specificity

    Highly expressed in testis, spleen, prostate, colon and heart, followed by moderate expression in thymus, ovary, small intestine, peripheral blood leukocytes, liver, skeletal muscle and pancreas. Weakly detected in kidney, placenta, brain and lung.
  • Sequence similarities

    Belongs to the very long-chain fatty acids dehydratase HACD family.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 3 hydroxyacyl CoA dehydratase 2 antibody
    • 3-hydroxyacyl-CoA dehydratase 2 antibody
    • HACD2 antibody
    • HACD2_HUMAN antibody
    • Protein tyrosine phosphatase like (proline instead of catalytic arginine) member b antibody
    • Protein tyrosine phosphatase like member B antibody
    • Protein-tyrosine phosphatase-like member B antibody
    • PTPLB antibody
    • Very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2 antibody
    see all

Images

  • All lanes : Anti-PTPLB antibody (ab237046) at 1/500 dilution

    Lane 1 : MCF7 (Human breast adenocarcinoma cell line) whole cell lysate
    Lane 2 : LO2 whole cell lysate

    Secondary
    All lanes : Goat polyclonal to Rabbit IgG at 1/10000 dilution
  • Paraffin-embedded human prostate cancer tissue stained for PTPLB using ab237046 at 1/100 dilution in immunohistochemical analysis.

  • MCF7 (Human breast adenocarcinoma cell line) cells stained for PTPLB (Green) using ab237046 at 1/100 dilution in ICC/IF, followed by an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L) secondary antibody.

References

ab237046 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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