• Product name

    Anti-PTPN13/FAP-1 antibody
  • Description

    Rabbit polyclonal to PTPN13/FAP-1
  • Host species

  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PTPN13/FAP-1 (internal sequence). NP_542414.
    Database link: Q12923

  • Positive control

    • Human cervical cancer and thyroid cancer tissues.
  • General notes

     This product was previously labelled as PTPN13




Our Abpromise guarantee covers the use of ab198882 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.


  • Relevance

    PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.
  • Cellular localization

  • Database links

  • Alternative names

    • APO1/CD95 (Fas) associated phosphatase antibody
    • DKFZp686J1497 antibody
    • FAP 1 antibody
    • FAP1 antibody
    • Fas associated phosphatase 1 antibody
    • Fas associated protein tyrosine phosphatase 1 antibody
    • HGNC:9646 antibody
    • hPTPE1 antibody
    • Phosphatase rip antibody
    • PNP 1 antibody
    • PNP1 antibody
    • Protein tyrosine phosphatase 1 Fas associated antibody
    • protein tyrosine phosphatase 1E antibody
    • Protein tyrosine phosphatase non receptor type 13 antibody
    • Protein tyrosine phosphatase nonreceptor type 13 antibody
    • Protein tyrosine phosphatase PTPL1 antibody
    • protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) antibody
    • PTP BAS antibody
    • PTP BL antibody
    • PTP E1 antibody
    • PTP1E antibody
    • PTPL 1 antibody
    • PTPL1 antibody
    • PTPLE antibody
    • PTPN 13 antibody
    • PTPN13 antibody
    • Tyrosine protein phosphatase non receptor type 13 antibody
    see all


  • Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling PTPN13/FAP-1 with ab198882 at 1/30 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling PTPN13/FAP-1 with ab198882 at 1/30 dilution.


This product has been referenced in:

  • Huang W  et al. Inhibition of Fas associated phosphatase 1 (Fap1) facilitates apoptosis of colon cancer stem cells and enhances the effects of oxaliplatin. Oncotarget 9:25891-25902 (2018). Read more (PubMed: 29899829) »
  • Wang Y  et al. Protein tyrosine phosphatase L1 inhibits high-grade serous ovarian carcinoma progression by targeting I?Ba. Onco Targets Ther 11:7603-7612 (2018). Read more (PubMed: 30464509) »
See all 3 Publications for this product

Customer reviews and Q&As

Western blot
Human Cell lysate - whole cell (Primary airway cells)
Gel Running Conditions
Reduced Denaturing
Loading amount
20 µg
Primary airway cells
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: RT°C

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Verified customer

Submitted Aug 02 2019

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