Overview

  • Product name

    Anti-PTPN18 antibody
  • Description

    Rabbit polyclonal to PTPN18
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human PTPN18 aa 1-210.
    Database link: Q99952

  • Positive control

    • WB: Rat heart tissue lysate. IHC-P: Human brain tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab230300 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Detects a band of approximately 50 kDa (predicted molecular weight: 50, 38 kDa).
IHC-P 1/20 - 1/200.

Target

  • Function

    Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
  • Tissue specificity

    Expressed in brain, colon and several tumor-derived cell lines.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization

    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • BDP 1 antibody
    • Brain derived phosphatase antibody
    • Brain-derived phosphatase antibody
    • Protein tyrosine phosphatase non receptor type 18 antibody
    • Protein tyrosine phosphatase non receptor type 18 brain derived antibody
    • PTN18_HUMAN antibody
    • PTP HSCF antibody
    • PTPN 18 antibody
    • PTPN18 antibody
    • Tyrosine protein phosphatase non receptor type 18 antibody
    • Tyrosine-protein phosphatase non-receptor type 18 antibody
    see all

Images

  • Anti-PTPN18 antibody (ab230300) at 1/1000 dilution + Rat heart tissue lysate

    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution

    Developed using the ECL technique.

    Predicted band size: 50, 38 kDa
    Observed band size: 50 kDa
    why is the actual band size different from the predicted?

  • Paraffin-embedded human brain tissue stained for PTPN18 with ab230300 at 1/100 dilution in immunohistochemical analysis.

References

ab230300 has not yet been referenced specifically in any publications.

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