Overview

  • Product name

  • Description

    Rabbit polyclonal to PTPRN2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide within Human PTPRN2 aa 206-255. The exact sequence is proprietary.
    Database link: Q92932

  • Positive control

    • WB: Extracts from NIH/3T3 cells. IHC-P: Human pancreas tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230360 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB 1/500 - 1/1000.

Target

  • Function

    Implicated in development of nervous system and pancreatic endocrine cells.
  • Tissue specificity

    Highest levels in brain and pancreas. Lower levels in trachea, prostate, stomach and spinal chord.
  • Sequence similarities

    Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Domain

    The cytoplasmic domain appears to contain the autoantigenic epitopes.
  • Post-translational
    modifications

    Appears to undergo multiple proteolytic cleavage at consecutive basic residues.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • IA 2beta antibody
    • IA2beta antibody
    • IAR antibody
    • IAR/receptor like protein tyrosine phosphatase antibody
    • ICAAR antibody
    • Islet cell autoantigen related protein antibody
    • Islet cell autoantigen-related protein antibody
    • Phogrin antibody
    • Protein tyrosine phosphatase receptor pi antibody
    • Protein tyrosine phosphatase, receptor type, N polypeptide 2 antibody
    • PTPR2_HUMAN antibody
    • Ptprn2 antibody
    • PTPRP antibody
    • R PTP N2 antibody
    • R-PTP-N2 antibody
    • Receptor-type tyrosine-protein phosphatase N2 antibody
    • Tyrosine phosphatase IA 2 beta antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human pancreas tissue stained for PTPRN2 with ab230360 at a 1/500 dilution in immunohistochemical analysis.

  • All lanes : Anti-PTPRN2 antibody (ab230360) at 1/500 dilution

    Lane 1 : NIH/3T3 (Mouse embyro fibroblast cell line) cell extracts
    Lane 2 : NIH/3T3 (Mouse embyro fibroblast cell line) cell extracts with immunizing peptide

    Developed using the ECL technique.

References

ab230360 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab230360.
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