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Anti-PUMA alpha antibody - C-terminal
Rabbit polyclonal to PUMA alpha - C-terminal
Predicted to work with:
Synthetic peptide corresponding to Human PUMA alpha aa 180-193 (C terminal).
NIH3T3, A549 and Hela cell lysates.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.05% Sodium azide Constituents: 50% Glycerol, 49% PBS (without Mg2+ and Ca2+)
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/2000. Predicted molecular weight: 21 kDa.
PUMA is localised to the mitochondria, binds BCL-2 and induces cytochrome C release and apoptosis in response to p53. PUMA is indeed an essential mediator of p53-dependent and -independent apoptosis in vivo, mediates the apoptotic response to p53 in colorectal cancer cells and is degraded during Chlamydia trachomatis infection
Cytoplasmic and Mitochondrial
BCL2 binding component 3 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"