Overview

  • Product name

  • Description

    Goat polyclonal to PUMA
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    C-DGGRPQRTVR

    , corresponding to internal sequence amino acids 178-187 of Human PUMA according to NP_001120712.1

  • Positive control

    • Peripheral Blood Lymphocytes lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab109548 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 21 kDa).

Target

  • Function

    Essential mediator of p53-dependent and p53-independent apoptosis.
  • Tissue specificity

    Ubiquitously expressed.
  • Sequence similarities

    Belongs to the Bcl-2 family.
  • Cellular localization

    Mitochondrion. Localized to the mitochondria in order to induce cytochrome c release.
  • Information by UniProt
  • Database links

  • Alternative names

    • BBC 3 antibody
    • Bbc3 antibody
    • BBC3_HUMAN antibody
    • BCL 2 binding component 3 antibody
    • Bcl-2-binding component 3 antibody
    • BCL2 binding component 3 antibody
    • JFY 1 antibody
    • JFY-1 antibody
    • JFY1 antibody
    • p53 up regulated modulator of apoptosis antibody
    • p53 up-regulated modulator of apoptosis antibody
    • p53 Upregulated Modulator of Apoptosis antibody
    • PUMA alpha antibody
    • PUMA/JFY1 antibody
    see all

Images

References

ab109548 has not yet been referenced specifically in any publications.

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