Overview

  • Product name

    Anti-PUMA antibody - N-terminal
    See all PUMA primary antibodies
  • Description

    Rabbit polyclonal to PUMA - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human PUMA (N terminal).
    Database link: Q9BXH1

  • Positive control

    • WB: K562 cell lysate. IHC-P: Human breast carcinoma and colon carcinoma tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab223618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 21 kDa.
IHC-P 1/100.

Target

  • Function

    Essential mediator of p53-dependent and p53-independent apoptosis.
  • Tissue specificity

    Ubiquitously expressed.
  • Sequence similarities

    Belongs to the Bcl-2 family.
  • Cellular localization

    Mitochondrion. Localized to the mitochondria in order to induce cytochrome c release.
  • Information by UniProt
  • Database links

  • Alternative names

    • BBC 3 antibody
    • Bbc3 antibody
    • BBC3_HUMAN antibody
    • BCL 2 binding component 3 antibody
    • Bcl-2-binding component 3 antibody
    • BCL2 binding component 3 antibody
    • JFY 1 antibody
    • JFY-1 antibody
    • JFY1 antibody
    • p53 up regulated modulator of apoptosis antibody
    • p53 up-regulated modulator of apoptosis antibody
    • p53 Upregulated Modulator of Apoptosis antibody
    • PUMA alpha antibody
    • PUMA/JFY1 antibody
    see all

Images

  • Human breast carcinoma tissue stained for PUMA using ab223618 at 1/100 dilution in immunohistochemical analysis. 

  • Anti-PUMA antibody - N-terminal (ab223618) at 1/500 dilution + K562 (human chronic myelogenous leukemia cell line from bone marrow) cell lysate

    Predicted band size: 21 kDa

  • Formalin-fixed human colon carcinoma tissue stained for PUMA using ab223618 at 1/10000 dilution in immunohistochemical analysis. Secondary Antibody: Goat Anti-Rabbit Biotin at 1/2000 for 1 hour at RT. Counterstain: Methyl Green.

References

ab223618 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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