• Product name
    Anti-Pumilio 2 antibody [EPR3813]
    See all Pumilio 2 primary antibodies
  • Description
    Rabbit monoclonal [EPR3813] to Pumilio 2
  • Host species
  • Specificity
    This antibody is predicted to not cross react with Pumilio 1.
  • Tested applications
    Suitable for: WB, IP, ICCmore details
    Unsuitable for: Flow Cyt or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Pumilio 2 aa 1-100. The exact sequence is proprietary.

  • Positive control
    • HeLa and 293T cell lysates
  • General notes



    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab92390 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    ICC: 1/100 - 1/250.

    IP: 1/10.
    WB: 1/5000 - 1/10000. Predicted molecular weight: 114 kDa.

    Is unsuitable for Flow Cyt or IHC-P.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
    • Tissue specificity
      Expressed in male germ cells of adult testis (at protein level). Highly expressed in testis and ovary. Predominantly expressed in stem cells and germ cells. Expressed at lower level in brain, heart, kidney, liver, muscle, placenta, intestine and stomach Expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen. Expressed in all fetal tissues tested.
    • Sequence similarities
      Contains 1 PUM-HD domain.
      Contains 8 pumilio repeats.
    • Domain
      The pumilio repeats mediate the association with RNA by packing together to form a right-handed superhelix that approximates a half doughnut. The number as well as the specific sequence of the repeats determine the specificity for target mRNAs.
    • Cellular localization
      Cytoplasm. Cytoplasmic granule. Cytoplasm > perinuclear region. The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules (By similarity). Colocalizes with NANOS1 and SNAPIN in the perinuclear region of germ cells.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ36528 antibody
      • KIAA0235 antibody
      • MGC138251 antibody
      • MGC138253 antibody
      • PUM 2 antibody
      • PUM2 antibody
      • PUM2_HUMAN antibody
      • PUMH 2 antibody
      • PUMH2 antibody
      • Pumilio (Drosphila) homolog 2 antibody
      • Pumilio homolog 2 (Drosophila) antibody
      • Pumilio homolog 2 antibody
      • Pumilio-2 antibody
      • Pumilio2 antibody
      • PUML2 antibody
      see all


    • All lanes : Anti-Pumilio 2 antibody [EPR3813] (ab92390) at 1/5000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate

      Lysates/proteins at 10 µg per lane.

      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 114 kDa
      Observed band size: 114 kDa


    This product has been referenced in:

    See 1 Publication for this product

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