Overview

  • Product name

    Puromycin aminonucleoside, Podocyte toxin
  • Description

    Podocyte toxin, induces ROS and oxidant-dependent DNA damage
  • Biological description

    Podocyte toxin, induces ROS and oxidant-dependent DNA damage in podocytes. Puromycin analogue that does not inhibit protein synthesis or induce DNA fragmentation. Antibiotic, antineoplastic and antimetabolite agent. Active in vivo and in vitro.
  • Purity

    > 98%
  • CAS Number

    58-60-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Marshall CB  et al. Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo. Kidney Int 70:1962-73 (2006). Read more (PubMed: 17035936) »
  • Gwinner W  et al. Reactive oxygen species and antioxidant defense in puromycin aminonucleoside glomerulopathy. J Am Soc Nephrol 8:1722-31 (1997). Read more (PubMed: 9355075) »
  • Chow SC  et al. Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis. Exp Cell Res 216:149-59 (1995). Read more (PubMed: 7813615) »
  • Bertram JF  et al. In vitro effects of puromycin aminonucleoside on the ultrastructure of rat glomerular podocytes. Cell Tissue Res 260:555-63 (1990). Read more (PubMed: 2372813) »

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