Key features and details
- Aminonuclease antibiotic agent. Protein biosynthesis inhibitor.
- CAS Number: 58-58-2
- Purity: > 98%
- Supplied in water (10 mg/ml)
- Form / State: Liquid
- Source: Synthetic
Product namePuromycin dihydrochloride (aqueous solution, sterile-filtered), aminonuclease antibiotic agent
DescriptionAminonuclease antibiotic agent. Protein biosynthesis inhibitor.
Biological descriptionAminonuclease antibiotic agent. Protein biosynthesis inhibitor. Induces cell cycle arrest in G2/M phase and apoptosis. Inhibits transport of proteins into mitochondria. Inhibits translation in vivo.
Also available as a solid (ab141453).
Chemical name(2S)-2-Amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide dihydrochloride
Storage instructionsStore at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
Solubility overviewSupplied in water (10 mg/ml)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146610 has not yet been referenced specifically in any publications.