Overview

  • Product name

    Pyranonigrin A, Antioxidant agent
  • Description

    Antioxidant agent
  • Biological description

    Antioxidant agent. Shows radical scavenging activity toward DPPH and superoxide. Suppresses TNF-α-induced VCAM-1 expression.
  • Purity

    > 95%
  • CAS Number

    773855-65-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2R)-2,6-Dihydroxy-5-[(E)-prop-1-enyl]-1,2-dihydropyrano[3,2-b]pyrrole-3,7-dione
  • Molecular weight

    223.18
  • Molecular formula

    C10H9NO5
  • PubChem identifier

    11379075
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C/C=C/C1=C(C(=O)C2=C(O1)C(=O)[C@H](N2)O)O
  • Source

    Aspergillus niger

  • Research areas

References

This product has been referenced in:

  • Riko R  et al. Studies on pyranonigrins-isolation of pyranonigrin E and biosynthetic studies on pyranonigrin A. J Antibiot (Tokyo) 67:179-81 (2014). Read more (PubMed: 24084681) »
  • Miyake Y  et al. Antioxidative pyranonigrins in rice mold starters and their suppressive effect on the expression of blood adhesion molecules. Biosci Biotechnol Biochem 72:1580-5 (2008). Read more (PubMed: 18540108) »
  • Miyake Y  et al. Isolation of the antioxidant pyranonigrin-A from rice mold starters used in the manufacturing process of fermented foods. Biosci Biotechnol Biochem 71:2515-21 (2007). Read more (PubMed: 17928714) »

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