Pyridostigmine bromide (Mestinon), acetylcholinesterase inhibitor (ab143028)

Overview

  • Product name

    Pyridostigmine bromide (Mestinon), acetylcholinesterase inhibitor
  • Description

    Reversible acetylcholinesterase inhibitor
  • CAS Number

    101-26-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (1-Methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate bromide
  • Molecular weight

    261.12
  • Molecular formula

    C9H13BrN2O2
  • PubChem identifier

    7550
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[N+]1=CC=CC(=C1)OC(=O)N(C)C.[Br-]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Sabino JP  et al. The treatment with pyridostigmine improves the cardiocirculatory function in rats with chronic heart failure. Auton Neurosci 173:58-64 (2013). Read more (PubMed: 23218833) »
  • Morsch M  et al. Pyridostigmine but not 3,4-diaminopyridine exacerbates ACh receptor loss and myasthenia induced in mice by muscle-specific kinase autoantibody. J Physiol 591:2747-62 (2013). Read more (PubMed: 23440963) »
  • Lataro RM  et al. Increase in parasympathetic tone by pyridostigmine prevents ventricular dysfunction during the onset of heart failure. Am J Physiol Regul Integr Comp Physiol 305:R908-16 (2013). Read more (PubMed: 23948774) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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