Key features and details
- Cell-permeable non-toxic hydrazone iron chelator
- CAS Number: 737-86-0
- Purity: > 99%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product namePyridoxal isonicotinoyl hydrazone (PIH), hydrazone iron chelator
DescriptionCell-permeable non-toxic hydrazone iron chelator
Cell-permeable non-toxic hydrazone iron chelator. Prevents iron-mediated oxyradical formation and minimizes tissue damage. Anticancer and apoptotic agent. Active in vitro.
See similar compounds
Chemical name2-[[3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide 4-pyridinecarboxylic acid
Storage instructionsStore at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145871 has been referenced in 1 publication.
- Hernández-Morales M et al. Lipid Oxidation Induced by RF Waves and Mediated by Ferritin Iron Causes Activation of Ferritin-Tagged Ion Channels. Cell Rep 30:3250-3260.e7 (2020). PubMed: 32160534