Product namePyridoxatin, MMP-2 inhibitor
DescriptionFree radical scavenger. MMP-2 inhibitor.
Biological descriptionFree radical scavenger (IC50 = 8 μM). MMP-2 inhibitor. Inhibits lipid peroxidation and DNA synthesis. Shows antifungal effects in vivo (IC50 = 6 μM).
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Signal transduction
- Nitric oxide & oxidative stress
This product has been referenced in:
- Wu B et al. Two new antibiotic pyridones produced by a marine fungus, Trichoderma sp. strain MF106. Mar Drugs 12:1208-19 (2014). Read more (PubMed: 24663111) »
- Cai P et al. 8-methyl-pyridoxatin: A novel N-hydroxy pyridone from fungus OS-F61800 that induces erythropoietin in human cells. J Nat Prod 62:397-9 (1999). Read more (PubMed: 10075801) »
- Teshima Y et al. Isolation and structural elucidation of pyridoxatin, a free radical scavenger of microbial origin. J Antibiot (Tokyo) 44:685-7 (1991). Read more (PubMed: 2071495) »