Key features and details
- Potent cell permeable HDAC1 inhibitor
- CAS Number: 382180-17-8
- Purity: > 95%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product namePyroxamide, HDAC1 inhibitor
DescriptionPotent cell permeable HDAC1 inhibitor
Biological descriptionPotent cell permeable HDAC1 inhibitor (IC50 = 100 nM). Induces p21/WAF1 and differentiation. Inhibits cell growth by inducing cell-cycle arrest and initiates apoptosis. Shows antitumor effects in vivo.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Epigenetics and Nuclear Signaling
- Chromatin Modifying Enzymes
- Class II / Hda1 Class
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144633 has not yet been referenced specifically in any publications.