Overview

  • Product name

    Pyrrolostatin, Lipid peroxidation inhibitor
  • Description

    Lipid peroxidation inhibitor
  • Biological description

    Lipid peroxidation inhibitor (IC50 = 49 μM). Free radical scavenger. Enhances angiogenesis in vivo.
  • Purity

    > 98%
  • CAS Number

    144314-68-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[(2E)-3,7-dimethylocta-2,6-dienyl]-1H-pyrrole-2-carboxylic acid
  • Molecular weight

    247.33
  • Molecular formula

    C15H21NO2
  • PubChem identifier

    5353914
  • Storage instructions

    Shipped on Dry Ice. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=CCCC(=CCC1=CNC(=C1)C(=O)O)C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Kato S  et al. Pyrrolostatin, a novel lipid peroxidation inhibitor from Streptomyces chrestomyceticus. Taxonomy, fermentation, isolation, structure elucidation and biological properties. J Antibiot (Tokyo) 46:892-9 (1993). Read more (PubMed: 8344870) »
  • Chekanov VS  et al. Biologic glue increases capillary ingrowth after cardiomyoplasty in an ischemic cardiomyopathy model. ASAIO J 42:M480-7 (0). Read more (PubMed: 8944927) »
  • Chekanov VS  et al. Angiogenesis in the latissimus dorsi muscle using different regimens of electrical stimulation and pharmaceutical support. ASAIO J 46:305-12 (0). Read more (PubMed: 10826742) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab143541.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up