Overview

  • Product name
    Q-DEVD-OPh, caspase-3 inhibitor
  • Description
    Potent, irreversible, cell-permeable caspase-3 inhibitor
  • Biological description
    Potent, irreversible, cell-permeable caspase-3 inhibitor
  • Purity
    > 90%
  • Chemical structure
    Chemical Structure

Properties

  • Molecular weight
    799.77
  • Molecular formula
    C38H43F2N5O12
  • Sequence
    DEVD (Modifications: N-terminal quinolyl; C-terminal OPh; Asp-1 = Asp(OMe); Glu-2 = Glu(OMe); Asp-4 = Asp(OMe))
  • PubChem identifier
    44135278
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    CC(C)C(C(=O)NC(CC(=O)OC)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C(CCC(=O)OC)NC(=O)C(CC(=O)OC)NC(=O)C2=NC3=CC=CC=C3C=C2
  • Source

    Synthetic

  • Research areas

Images

  • Titration of the Caspase 3 specific inhibitor Q-DEVD-OPh (ab142037) (duplicates; +/- SD).
  • Functional assays: Caspase 9 Inhibitor Drug Detection Kit (ab102497) Titration of the caspase inhibitors Z-VAD(OMe)-FMK (ab120487) and Q-LEHD-Oph (ab142039) (duplicates; +/- SD).

References

ab142037 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"
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