Overview

  • Product name
    Anti-QPCT antibody - C-terminal
    See all QPCT primary antibodies
  • Description
    Rabbit polyclonal to QPCT - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human QPCT aa 314-343 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q16769

  • Positive control
    • CEM cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab173108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

Target

  • Function
    Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.
  • Sequence similarities
    Belongs to the glutaminyl-peptide cyclotransferase family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5730422A13Rik antibody
    • EC antibody
    • GCT antibody
    • Glutaminyl cyclase antibody
    • Glutaminyl peptide cyclotransferase antibody
    • Glutaminyl tRNA cyclotransferase antibody
    • Glutaminyl-peptide cyclotransferase antibody
    • Glutaminyl-tRNA cyclotransferase antibody
    • Glutamyl cyclase antibody
    • QC antibody
    • qpct antibody
    • QPCT_HUMAN antibody
    • sQC antibody
    see all

Images

  • Anti-QPCT antibody - C-terminal (ab173108) at 1/100 dilution + CEM cell line lysate at 35 µg

    Predicted band size: 41 kDa

References

ab173108 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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