QS11, ARFGAP1 inhibitor (ab141408)
Key features and details
- ARFGAP1 inhibitor. Wnt/β-catenin pathway modulator.
- CAS Number: 944328-88-5
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
QS11, ARFGAP1 inhibitor -
Description
ARFGAP1 inhibitor. Wnt/β-catenin pathway modulator. -
Purity
> 98% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 1680 QS11. 1680-5 is the same size as the 5 mg size of ab141408.
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CAS Number
944328-88-5 -
Chemical structure
Properties
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Chemical name
(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol -
Molecular weight
567.68 -
Molecular formula
C36H33N5O2 -
PubChem identifier
42623900 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1CC2=C(C1)C=C(C=C2)OC3=NC4=C(C(=N3)N[C@@H](CC5=CC=CC=C5)CO)N=CN4CC6=CC=C(C=C6)C7=CC=CC=C7 -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab141408 has been referenced in 1 publication.
- Li W et al. Annexin A2 is a Robo4 ligand that modulates ARF6 activation-associated cerebral trans-endothelial permeability. J Cereb Blood Flow Metab 39:2048-2060 (2019). PubMed: 29786451