Overview

  • Product name

  • Description

    Rabbit polyclonal to QSOX2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Hamster, Cow, Dog, Monkey, Gorilla, Opossum, Bat
  • Immunogen

    Synthetic 20 amino acid peptide from the internal region of Human QSOX2 (NP_859052).

  • Positive control

    • Human heart and adrenal tissues

Properties

Applications

Our Abpromise guarantee covers the use of ab133399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 20 µg/ml.

Target

  • Function

    Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. Also seems to play a role in regulating the sensitization of neuroblastoma cells for interferon-gamma-induced apoptosis.
  • Tissue specificity

    Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles.
  • Sequence similarities

    Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
    Contains 1 ERV/ALR sulfhydryl oxidase domain.
    Contains 1 thioredoxin domain.
  • Cellular localization

    Membrane. Secreted. Cell membrane. Nucleus membrane. Seems to be predominantly targeted to the nuclear and outer plasma membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • DKFZp762A2013 antibody
    • Neuroblastoma-derived sulfhydryl oxidase antibody
    • QSCN6L1 antibody
    • QSOX2 antibody
    • QSOX2_HUMAN antibody
    • Quiescin Q6 like 1 antibody
    • Quiescin Q6 sulfhydryl oxidase 2 antibody
    • Quiescin Q6-like protein 1 antibody
    • SOXN antibody
    • Sulfhydryl oxidase 2 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labelling QSOX2 with ab133399 at 20 µg/ml, using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human adrenal tissue labelling QSOX2 with ab133399 at 20 µg/ml, using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab133399 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab133399.
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