Overview

  • Product name

    Quinapril hydrochloride, ACE inhibitor
  • Description

    ACE inhibitor
  • Biological description

    ACE inhibitor (Ki = 20 μM). Selective for tissue and circulatory compartments of the renin-angiotensin-aldosterone system. Anti-hypertensive effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    82586-55-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3S)-2-[(2S)-2-[[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride
  • Molecular weight

    474.99
  • Molecular formula

    C25H30N2O5.HCl
  • PubChem identifier

    54891
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Fateev MM  et al. Heart rate variability in conscious and anesthetized rats under the action of angiotensin converting enzyme inhibitors. Bull Exp Biol Med 152:590-4 (2012). Read more (PubMed: 22803141) »
  • Hiller KH  et al. Tissue ACE inhibition improves microcirculation in remote myocardium after coronary stenosis: MR imaging study in rats. Microvasc Res 80:484-90 (2010). Read more (PubMed: 20570682) »
  • Gryglewski RJ & Mackiewicz Z Vane's blood-bathed organ technique adapted to examine the endothelial effects of cardiovascular drugs in vivo. Pharmacol Rep 62:462-7 (0). Read more (PubMed: 20631409) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab142940.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up