• Product name
    Anti-Quinolinic acid antibody
  • Description
    Rabbit polyclonal to Quinolinic acid
  • Host species
  • Specificity
    This antibody targets conjugated quinolinic acid, it doesn't recognize free quinolinic acid.
  • Tested applications
    Suitable for: IHC-Fr, IHC-Pmore details
  • Immunogen

    Chemical/ Small Molecule corresponding to Quinolinic acid conjugated to Bovine Serum Albumin (BSA).



Our Abpromise guarantee covers the use of ab37106 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration. PubMed: 21831269


  • Relevance
    Quinolinic acid is a naturally occurring toxin in the central nervous system believed to play a role in AIDS dementia complex. A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated csf levels of quinolinic acid are significantly correlated with the severity of neuropsychological deficits in patients who have aids.
  • Alternative names
    • Pyridine 23 dicarboxylic Acid antibody


This product has been referenced in:
  • Busse M  et al. Decreased quinolinic acid in the hippocampus of depressive patients: evidence for local anti-inflammatory and neuroprotective responses? Eur Arch Psychiatry Clin Neurosci 265:321-9 (2015). Read more (PubMed: 25409655) »
  • Steiner J  et al. Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission? J Neuroinflammation 8:94 (2011). IHC-P ; Human . Read more (PubMed: 21831269) »

See all 2 Publications for this product

Customer reviews and Q&As

Thank you very much for your interest in ab85518 and ab37106.

To our knowledge, ab85518 and ab37106 have not been tested in flow cytometry.If however you would like to test this,I can offer a discount off a future purchase if you buy ab85518...

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I don't think it will be possible to detect free quinolinic acid by ELISA using ab37106 and ab88518 in a sELISA. These antibodies will not detect free quinolinic acid and they have never been tested together in a sELISA so their epitopes are...

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These antibodies will not recognize free quinolinic acid. They will only recognize the quinolinic acid in the presence of gluteraldehyde, either as part of the protein carrier linkage, or as a component in the tissue profusion step.


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I am happy to confirm that both antibodies are recognizing t to their target in dependent of the species that sample originates from.

The targets are not proteins or peptides but are chemical compounds (metabolite) that have the sam...

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Using a quinolinic acid adsorbed on bovine serum albumin, antibody specificity was performed with an ELISA test by competition experiments with the following compounds:

Compound Cross reactivity*


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Thank you for your inquiry.

I can confirm that ab37106 is tested and guaranteed for ELISA, IHC-Fr (PFA fixed)andIHC-P.

All information we have we state on the datasheet.

Unfortunately, we do not currently have more inform...

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Thank you for your enquiry.

I can confirm that ab37106Quinolinic acid antibody is sold as whole antiserum. Unpurified antibodies, such as those sole as whole antiserum, will not have a concentration stated on the datasheet. Antibody concentr...

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Thank you for your enquiry. I am afraid that we do not know the exact concentration of this product since unpurified antibody preparations vary significantly in specific antibody concentration. However, there are some “typical ranges”, which can be ...

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