Key features and details
- Na+ channel blocker. 1 ml water soluble pack.
- CAS Number: 5369-03-9
- Purity: > 99%
- Soluble in 1 ml water to give specified mM/ml concentration
- Form / State: Solid
- Source: Synthetic
Product nameQX-314 chloride (N-Ethyllidocaine chloride) (mM/ml), Na+ channel blocker
DescriptionNa+ channel blocker. 1 ml water soluble pack.
- N-Ethyllidocaine chloride
A membrane impermeable quaternary lidocaine derivative. Blocks voltage-sensitive Na+ channels.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more.
Chemical nameN-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium chloride
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in 1 ml water to give specified mM/ml concentration
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144493 has been referenced in 4 publications.
- Perez-Rosello T et al. Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis. J Neurosci 33:9259-72 (2013). PubMed: 23719795
- Mitchell VA et al. Cholecystokinin exerts an effect via the endocannabinoid system to inhibit GABAergic transmission in midbrain periaqueductal gray. Neuropsychopharmacology 36:1801-10 (2011). PubMed: 21525858
- Bagnall MW et al. Multiple clusters of release sites formed by individual thalamic afferents onto cortical interneurons ensure reliable transmission. Neuron 71:180-94 (2011). PubMed: 21745647
- Case DT & Gillespie DC Pre- and postsynaptic properties of glutamatergic transmission in the immature inhibitory MNTB-LSO pathway. J Neurophysiol 106:2570-9 (2011). PubMed: 21832038