Key features and details
- Selective K+/Cl--cotransporter inhibitor
- CAS Number: 81166-47-4
- Purity: > 98%
- Soluble in ethanol and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Product nameR-(+)-DIOA (R(+)-Butylindazone), K+/Cl--cotransporter inhibitor
DescriptionSelective K+/Cl--cotransporter inhibitor
Biological descriptionSelective K+/Cl--cotransporter inhibitor. Does not affect the bumetanide-sensitive Na+/K+/Cl--cotransport system. Suppresses osteoclastic pit formation and Cl- and H+ extrusion.
Chemical name2-[[(2S)-2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-3H-inden-5-yl]oxy]acetic acid
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol and in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Receptors & Transporters
- Ion pumps / transporter
- Na+/2Cl-/K+ cotransporter
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab145200 has not yet been referenced specifically in any publications.