Overview

  • Product name

    (R)-Bicalutamide, androgen receptor antagonist
  • Description

    Non-steroidal androgen receptor antagonist
  • Biological description

    Non-steroidal androgen receptor antagonist. (R)-Enantiomer of antiandrogen Bicalutamide (Asc 1249). Stimulates AR-mediated transcription. Orally active.
  • Purity

    > 98%
  • CAS Number

    113299-40-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Hwang DJ  et al. Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer. Bioorg Med Chem 14:6525-38 (2006). Read more (PubMed: 16828557) »
  • Bohl CE  et al. Structural basis for accommodation of nonsteroidal ligands in the androgen receptor. J Biol Chem 280:37747-54 (2005). Read more (PubMed: 16129672) »
  • Mukherjee A  et al. Affinity labeling of the androgen receptor with nonsteroidal chemoaffinity ligands. Biochem Pharmacol 58:1259-67 (1999). Read more (PubMed: 10487527) »

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