(R)-Tomoxetine hydrochloride, norepinephrine reuptake inhibitor (ab120758)

Overview

  • Product name

    (R)-Tomoxetine hydrochloride, norepinephrine reuptake inhibitor
  • Description

    Potent, selective norepinephrine reuptake inhibitor
  • Alternative names

    • Atomoxetine hydrochloride
  • Biological description

    Potent and selective norepinephrine reuptake inhibitor. Ki values are 5, 77 and 1451 nM for inhibitors NET, DAT and SERT, respectively. Increases extraneuronal norepinephrine and dopamine levels within brain regions associated with Attention Deficit Hyperactivity Disorder.
  • Purity

    > 99%
  • CAS Number

    82248-59-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Swanson CJ  et al. Effect of the attention deficit/hyperactivity disorder drug atomoxetine on extracellular concentrations of norepinephrine and dopamine in several brain regions of the rat. Neuropharmacology 50:755-60 (2006). Read more (PubMed: 16427661) »
  • Bymaster FP  et al. Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology 27:699-711 (2002). Read more (PubMed: 12431845) »

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