Key features and details
- Mouse polyclonal to RAB11B
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RAB11B antibody
See all RAB11B primary antibodies
DescriptionMouse polyclonal to RAB11B
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Full length protein corresponding to Human RAB11B aa 1-218. Full length protein, corresponding to amino acids 1-218 of Human Rab11b (NP_004209).
MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFAT RSIQVDGKTIKAQIWDTAGQERYRRITSAYYRGAVGALLVYDIAKHLTYE NVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSF IETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISV PPTTDGQKPNKLQCCQNL
Database link: Q15907
- Lysate of 293T cells transfected with Rab11b.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.20
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab168559 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa.|
FunctionThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.
Sequence similaritiesBelongs to the small GTPase superfamily. Rab family.
modificationsCitrullinated by PADI4.
Cellular localizationRecycling endosome membrane. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasmic vesicle, phagosome membrane. Recruited to phagosomes containing S.aureus.
- Information by UniProt
- GTP-binding protein ypt3 antibody
- H YPT3 antibody
- RAB11B antibody
ab168559 has not yet been referenced specifically in any publications.