Anti-RAB23 antibody (ab192420)
Key features and details
- Rabbit polyclonal to RAB23
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-RAB23 antibody -
Description
Rabbit polyclonal to RAB23 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide within Human RAB23. The exact sequence is proprietary.
Database link: Q9ULC3 -
Positive control
- MCF7 whole cell lysate, HEK293T whole cell lysate, NIH 3T3 whole cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Purity is > 95% (by SDS-PAGE). -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab192420 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/5. Predicted molecular weight: 27 kDa.
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Notes |
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WB
1/5. Predicted molecular weight: 27 kDa. |
Target
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Involvement in disease
Defects in RAB23 are the cause of acrocephalopolysyndactyly type 2 (ACPS2) [MIM:201000]. A syndrome characterized by craniosynostosis, polysyndactyly, obesity, and cardiac defects. -
Sequence similarities
Belongs to the small GTPase superfamily. Rab family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 51715 Human
- Entrez Gene: 19335 Mouse
- Omim: 606144 Human
- SwissProt: Q9ULC3 Human
- SwissProt: P35288 Mouse
- Unigene: 555016 Human
- Unigene: 86744 Mouse
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Alternative names
- DKFZp781H0695 antibody
- HSPC137 antibody
- MGC8900 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (1)
ab192420 has been referenced in 1 publication.
- Zhang W et al. Rab23 promotes the cisplatin resistance of ovarian cancer via the Shh-Gli-ABCG2 signaling pathway. Oncol Lett 15:5155-5160 (2018). PubMed: 29552151