Key features and details
- Rabbit polyclonal to RAB26
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RAB26 antibody
See all RAB26 primary antibodies
DescriptionRabbit polyclonal to RAB26
The antibody detects endogenous levels of total RAB26 protein.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human RAB26 (internal sequence).
Database link: Q9ULW5
- WB: MCF7 and A375 cells; IHC: Human gasrtic and ovarian cancer tissue.
Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab198202 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/25 - 1/100.|
|WB||1/200 - 1/1000. Predicted molecular weight: 28 kDa.|
FunctionParticipates in exocrine secretion: regulates the secretion of acinar granules in the parotid gland.
Tissue specificityPredominantly expressed in brain.
Sequence similaritiesBelongs to the small GTPase superfamily. Rab family.
Cellular localizationCell membrane.
- Information by UniProt
- CATX-8 antibody
- RAB11c antibody
- Rab26 antibody
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using ab198202 at dilution 1/60.
Immunohistochemical analysis of paraffin-embedded Human gasrtic cancer tissue using ab198202 at dilution 1/60.
All lanes : Anti-RAB26 antibody (ab198202) at 1/200 dilution
Lane 1 : MCF7 cells
Lane 2 : A375 cells
Lysates/proteins at 40 µg per lane.
All lanes : Goat anti rabbit IgG at 1/8000 dilution
Predicted band size: 28 kDa
Exposure time: 5 seconds
ab198202 has been referenced in 1 publication.
- Liu N et al. SNRPB promotes the tumorigenic potential of NSCLC in part by regulating RAB26. Cell Death Dis 10:667 (2019). PubMed: 31511502