• Product name

  • Description

    Rabbit polyclonal to RAB3GAP2
  • Host species

  • Specificity

    ab110462 detects endogenous levels of total RAB3GAP2 protein.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from an internal region of Human RAB3GAP2 (UniProt ID: Q9H2M9).

  • Positive control

    • Human breast carcinoma tissue; extracts from COS cells



Our Abpromise guarantee covers the use of ab110462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 155 kDa (predicted molecular weight: 156 kDa).
IHC-P 1/50 - 1/100. Antigen retrieval is heat-mediated, citrate buffer pH 6.0. A pressure cooker was used for about 5 minutes.


  • Relevance

    RAB3GAP2 is a regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. It is required for normal eye and brain development and may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
  • Cellular localization

    Cytoplasmic. Note: In neurons, it is enriched in the synaptic soluble fraction.
  • Database links

  • Alternative names

    • DKFZp434D245 antibody
    • FLJ14579 antibody
    • KIAA0839 antibody
    • p150 antibody
    • Rab3 GAP p150 antibody
    • Rab3 GAP regulatory subunit antibody
    • Rab3 GAP150 antibody
    • Rab3 GTPase activating protein 150 kDa subunit antibody
    • Rab3 GTPase activating protein non catalytic subunit antibody
    • RAB3 GTPase activating protein subunit 2 (non catalytic) antibody
    • RAB3 GTPase activating protein subunit 2 antibody
    • RAB3GAP150 antibody
    • RGAP iso antibody
    • RP11 568G11.1 antibody
    see all


  • All lanes : Anti-RAB3GAP2 antibody (ab110462) at 1/500 dilution

    Lane 1 : Extracts from COS cells
    Lane 2 : Extracts from COS cells, treated with the synthesized peptide

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 156 kDa
    Observed band size: 155 kDa
    why is the actual band size different from the predicted?

  • ab110462, at a 1/50 dilution, staining RAB3GAP2 in paraffin embedded Human breast carcinoma tissue by Immunohistochemistry, in the absence (left image) or presence (right image) of the synthesized peptide.


ab110462 has not yet been referenced specifically in any publications.

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