Key features and details
- Rabbit polyclonal to Rabenosyn 5 - C-terminal
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Rabenosyn 5 antibody - C-terminal
See all Rabenosyn 5 primary antibodies
DescriptionRabbit polyclonal to Rabenosyn 5 - C-terminal
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to a region within the C terminal amino acids 721-784 of the Human Rabenosyn 5 protein (Q9H1K0).
- WB: A431, H1299, HeLa and HepG2 whole cell lysates.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab155247 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 89 kDa.|
FunctionRab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
Sequence similaritiesContains 1 C2H2-type zinc finger.
Contains 1 FYVE-type zinc finger.
Contains 1 UIM (ubiquitin-interacting motif) repeat.
Cellular localizationCell membrane. Early endosome membrane.
- Information by UniProt
- 110 kDa protein antibody
- FYVE finger containing Rab5 effector protein Rabenosyn 5 antibody
- FYVE finger-containing Rab5 effector protein rabenosyn-5 antibody
ab155247 has been referenced in 1 publication.
- Frittoli E et al. A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination. J Cell Biol 206:307-28 (2014). PubMed: 25049275