Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab224408 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/100 - 1/250. Predicted molecular weight: 20 kDa.|
FunctionSmall GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 (PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 (PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25.
Involvement in diseaseBardet-Biedl syndrome 19
Sequence similaritiesBelongs to the small GTPase superfamily. Rab family.
Cellular localizationCell projection, cilium.
- Information by UniProt
- BBS19 antibody
- Ift27 antibody
- IFT27_HUMAN antibody
All lanes : Anti-RABL4 antibody (ab224408) at 1/100 dilution
Lane 1 : Vector only transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate
Lane 2 : RABL4 overexpression HEK-293T (co-expressed with a C terminal myc-DDK tag, ~3.1 kDa) cell lysate
Predicted band size: 20 kDa
ab224408 has not yet been referenced specifically in any publications.