Ractopamine hydrochloride,  beta1 and beta2-adrenoceptor agonist (ab142536)

Overview

  • Product name

    Ractopamine hydrochloride,  beta1 and beta2-adrenoceptor agonist
  • Description

    Potent β1 and β2-adrenoceptor agonist
  • Biological description

    Potent β1 and β2-adrenoceptor agonist. Increases force and rate of atrial contractions (EC50 = 100 nM). Relaxes KCl-contracted smooth muscle (EC50 = 60 nM). Orally active in vivo.
  • Purity

    > 98%
  • CAS Number

    90274-24-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-[3-[[2-Hydroxy-2-(4-hydroxyphenyl)ethyl]amino]butyl]phenol hydrochloride
  • Molecular weight

    337.84
  • Molecular formula

    C18H23NO3.HCl
  • PubChem identifier

    14010333
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(CCC1=CC=C(C=C1)O)NCC(C2=CC=C(C=C2)O)O.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Mills SE  et al. Stereoselectivity of porcine beta-adrenergic receptors for ractopamine stereoisomers. J Anim Sci 81:122-9 (2003). Read more (PubMed: 12597381) »
  • Mills SE  et al. Beta-adrenergic receptor subtypes that mediate ractopamine stimulation of lipolysis. J Anim Sci 81:662-8 (2003). Read more (PubMed: 12661646) »
  • Colbert WE  et al. Beta-adrenoceptor profile of ractopamine HCl in isolated smooth and cardiac muscle tissues of rat and guinea-pig. J Pharm Pharmacol 43:844-7 (1991). Read more (PubMed: 1687583) »

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