Overview

  • Product name

    Anti-RAD3 antibody
  • Description

    Rabbit polyclonal to RAD3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Saccharomyces cerevisiae
  • Immunogen

    Recombinant fragment, corresponding to a region within N terminal amino acids 1-147 of Saccharomyces cerevisiae RAD3 (P06839).

  • Positive control

    • Saccharomyces cerevisiae cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab127891 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 90 kDa.

Target

  • Function

    ATP-dependent DNA helicase involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Necessary for excision of pyrimidine dimers. Also unwinds DNA/RNA duplexes. Plays an essential role in the cell viability. Involved in the maintenance of the fidelity of DNA replication. Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.
  • Sequence similarities

    Belongs to the helicase family. RAD3/XPD subfamily.
    Contains 1 helicase ATP-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

    • Alternative names

      • DNA repair helicase RAD3 antibody
      • General transcription and DNA repair factor IIH subunit RAD3 antibody
      • rad3 antibody
      • RAD3_YEAST antibody
      • Rad3p antibody
      • REM1 antibody
      • TFIIH subunit RAD3 antibody
      see all

    Images

    • Anti-RAD3 antibody (ab127891) at 1/2000 dilution + Saccharomyces cerevisiae whole cell lysate at 10 µg

      Predicted band size: 90 kDa



      7.5% SDS Page

    References

    ab127891 has not yet been referenced specifically in any publications.

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