Key features and details
- Rabbit polyclonal to RAD3
- Suitable for: WB
- Reacts with: Saccharomyces cerevisiae
- Isotype: IgG
Product nameAnti-RAD3 antibody
DescriptionRabbit polyclonal to RAD3
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Saccharomyces cerevisiae
Recombinant fragment, corresponding to a region within N terminal amino acids 1-147 of Saccharomyces cerevisiae RAD3 (P06839).
- Saccharomyces cerevisiae cell lysate.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab127891 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 90 kDa.|
FunctionATP-dependent DNA helicase involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Necessary for excision of pyrimidine dimers. Also unwinds DNA/RNA duplexes. Plays an essential role in the cell viability. Involved in the maintenance of the fidelity of DNA replication. Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.
Sequence similaritiesBelongs to the helicase family. RAD3/XPD subfamily.
Contains 1 helicase ATP-binding domain.
- Information by UniProt
- DNA repair helicase RAD3 antibody
- General transcription and DNA repair factor IIH subunit RAD3 antibody
- rad3 antibody
ab127891 has not yet been referenced specifically in any publications.