Key features and details
- Rabbit polyclonal to Rad51L1/RAD51B
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Rad51L1/RAD51B antibody
DescriptionRabbit polyclonal to Rad51L1/RAD51B
Tested applicationsSuitable for: ICC/IFmore details
Species reactivityReacts with: Human
- ICC/IF: MCF7 cells
This product was previously labelled as Rad51L1
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab247110 in the following tested applications.
|ICC/IF||Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100.
FunctionInvolved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Tissue specificityExpressed in a wide range of tissues.
Involvement in diseaseNote=A chromosomal aberration involving RAD51L1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with HMGA1.
Note=A chromosomal aberration involving RAD51L1 is found in uterine leiomyoma. Translocation t(12;14)(q15;q23-24) with HMGA2.
Sequence similaritiesBelongs to the RecA family. RAD51 subfamily.
- Information by UniProt
- DNA repair protein RAD51 homolog 2 antibody
- hREC2 antibody
- MGC34245 antibody
ab247110 has not yet been referenced specifically in any publications.