Anti-RAET1E antibody [79/6/13/16] (ab95202)

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Key features and details

  • Mouse monoclonal [79/6/13/16] to RAET1E
  • Reacts with: Human
  • Isotype: IgG2a

Overview

  • Product name

    Anti-RAET1E antibody [79/6/13/16]
    See all RAET1E primary antibodies

  • Description

    Mouse monoclonal [79/6/13/16] to RAET1E

  • Host species

    Mouse

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Recombinant fragment corresponding to Human RAET1E aa 33-227 (N terminal).

  • Positive control

    • Stable RAET1E cell line

  • General notes

     This product was previously labelled as ULBP4

     

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

  • Storage buffer

    Constituent: PBS
  • Concentration information loading...

  • Purity

    Protein A/G purified

  • Clonality

    Monoclonal

  • Clone number

    79/6/13/16

  • Isotype

    IgG2a

  • Research areas

Target

  • Function

    Ligand for the NKG2D receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes.

  • Tissue specificity

    Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid.

  • Sequence similarities

    Belongs to the MHC class I family.

  • Cellular localization

    Secreted and Membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • bA350J20.7 antibody
      • LETAL antibody
      • Lymphocyte effector toxicity activation ligand antibody
      • MGC125308 antibody
      • MGC125309 antibody
      • N2DL-4 antibody
      • N2DL4 antibody
      • N2DL4_HUMAN antibody
      • NKG2D ligand 4 antibody
      • NKG2D ligand 4 precursor antibody
      • NKG2DL4 antibody
      • RAE-1-like transcript 4 antibody
      • RAET1E antibody
      • RAET1E2 antibody
      • Retinoic acid early transcript 1E antibody
      • RL-4 antibody
      see all

    References (3)

    Publishing research using ab95202? Please let us know so that we can cite the reference in this datasheet.

    ab95202 has been referenced in 3 publications.

    • Song M  et al. Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response. Oncoimmunology 9:1746148 (2020). PubMed: 32363114
    • Chitadze G  et al. In-depth immunophenotyping of patients with glioblastoma multiforme: Impact of steroid treatment. Oncoimmunology 6:e1358839 (2017). PubMed: 29147621
    • Mimura K  et al. Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer. Int J Cancer 135:1390-8 (2014). PubMed: 24615495

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