Anti-RAET1E antibody [79/6/13/16] (ab95202)
Key features and details
- Mouse monoclonal [79/6/13/16] to RAET1E
- Reacts with: Human
- Isotype: IgG2a
Overview
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Product name
Anti-RAET1E antibody [79/6/13/16]
See all RAET1E primary antibodies -
Description
Mouse monoclonal [79/6/13/16] to RAET1E -
Host species
Mouse -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human RAET1E aa 33-227 (N terminal).
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Positive control
- Stable RAET1E cell line
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General notes
This product was previously labelled as ULBP4
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: PBS -
Concentration information loading...
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Purity
Protein A/G purified -
Clonality
Monoclonal -
Clone number
79/6/13/16 -
Isotype
IgG2a -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Target
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Function
Ligand for the NKG2D receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes. -
Tissue specificity
Predominantly expressed in the skin, but also expressed in testis and trachea. Up-regulated in tumor cells of different origins. Expression progressively decreased after treatment of tumor cells with retinoic acid. -
Sequence similarities
Belongs to the MHC class I family. -
Cellular localization
Secreted and Membrane. - Information by UniProt
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Database links
- Entrez Gene: 135250 Human
- Omim: 609243 Human
- SwissProt: Q8TD07 Human
- Unigene: 511818 Human
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Alternative names
- bA350J20.7 antibody
- LETAL antibody
- Lymphocyte effector toxicity activation ligand antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab95202 has been referenced in 3 publications.
- Song M et al. Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response. Oncoimmunology 9:1746148 (2020). PubMed: 32363114
- Chitadze G et al. In-depth immunophenotyping of patients with glioblastoma multiforme: Impact of steroid treatment. Oncoimmunology 6:e1358839 (2017). PubMed: 29147621
- Mimura K et al. Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer. Int J Cancer 135:1390-8 (2014). PubMed: 24615495