Anti-RAGE antibody (ab3611)

Rabbit polyclonal RAGE antibody. Validated in WB, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human. Cited in 53 publication(s). Independently reviewed in 14 review(s).

Publishing research using ab3611? Please let us know so that we can cite the reference in this datasheet.

ab3611 has been referenced in 54 publications.

  • Chen HH  et al. Antihypertensive Potential of Coenzyme Q10 via Free Radical Scavenging and Enhanced Akt-nNOS Signaling in the Nucleus Tractus Solitarii in Rats. Mol Nutr Food Res 63:e1801042 (2019). PubMed: 30668894
  • Chen YH  et al. AGE/RAGE-Induced EMP Release via the NOX-Derived ROS Pathway. J Diabetes Res 2018:6823058 (2018). PubMed: 29744367
  • Xu X  et al. ERK1/2/mTOR/Stat3 pathway-mediated autophagy alleviates traumatic brain injury-induced acute lung injury. Biochim Biophys Acta 1864:1663-1674 (2018). WB . PubMed: 29466698
  • Xiong J  et al. Phosphorylation of low density lipoprotein receptor-related protein 6 is involved in receptor for advanced glycation end product-mediated ß-catenin stabilization in a toluene diisocyanate-induced asthma model. Int Immunopharmacol 59:187-196 (2018). PubMed: 29656209
  • Hartz AMS  et al. Preventing P-gp Ubiquitination Lowers Aß Brain Levels in an Alzheimer's Disease Mouse Model. Front Aging Neurosci 10:186 (2018). PubMed: 29997495
  • Zhang M  et al. Blockade of receptors of advanced glycation end products ameliorates diabetic osteogenesis of adipose-derived stem cells through DNA methylation and Wnt signalling pathway. Cell Prolif 51:e12471 (2018). PubMed: 30014569
  • Fuller KNZ  et al. A single high-fat meal alters human soluble RAGE profiles and PBMC RAGE expression with no effect of prior aerobic exercise. Physiol Rep 6:e13811 (2018). PubMed: 30047241
  • Shi X  et al. Neuroprotective effects of SMTP-44D in mice stroke model in relation to neurovascular unit and trophic coupling. J Neurosci Res 96:1887-1899 (2018). PubMed: 30242877
  • Zhang H  et al. Rosuvastatin reduces the pro-inflammatory effects of adriamycin on the expression of HMGB1 and RAGE in rats. Int J Mol Med 42:3415-3423 (2018). PubMed: 30320373
  • Qian F  et al. HMGB1-RAGE signaling facilitates Ras-dependent Yap1 expression to drive colorectal cancer stemness and development. Mol Carcinog N/A:N/A (2018). PubMed: 30456802
  • Liu C  et al. Aqueous Extract of Mori Folium Exerts Bone Protective Effect Through Regulation of Calcium and Redox Homeostasis via PTH/VDR/CaBP and AGEs/RAGE/Nox4/NF-?B Signaling in Diabetic Rats. Front Pharmacol 9:1239 (2018). PubMed: 30459613
  • Lawrimore CJ & Crews FT Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2. Alcohol Clin Exp Res 41:939-954 (2017). PubMed: 28273337
  • Hou B  et al. Salvianolic Acid A Protects Against Diabetic Nephropathy through Ameliorating Glomerular Endothelial Dysfunction via Inhibiting AGE-RAGE Signaling. Cell Physiol Biochem 44:2378-2394 (2017). PubMed: 29262395
  • Pellegrini L  et al. HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma. Oncotarget 8:22649-22661 (2017). PubMed: 28186988
  • Wang L  et al. Effect of rosiglitazone on amyloid precursor protein processing and Aß clearance in streptozotocin-induced rat model of Alzheimer's disease. Iran J Basic Med Sci 20:474-480 (2017). WB ; Rat . PubMed: 28656081
  • Saito S  et al. Taxifolin inhibits amyloid-ß oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy. Acta Neuropathol Commun 5:26 (2017). PubMed: 28376923
  • Liu Y  et al. S100P is associated with proliferation and migration in nasopharyngeal carcinoma. Oncol Lett 14:525-532 (2017). PubMed: 28693201
  • Gao H  et al. Pioglitazone Attenuates Atherosclerosis in Diabetic Mice by Inhibition of Receptor for Advanced Glycation End-Product (RAGE) Signaling. Med Sci Monit 23:6121-6131 (2017). IHC-P ; Mouse . PubMed: 29278639
  • Ohtsu A  et al. Advanced glycation end products and lipopolysaccharides stimulate interleukin-6 secretion via the RAGE/TLR4-NF-?B-ROS pathways and resveratrol attenuates these inflammatory responses in mouse macrophages. Exp Ther Med 14:4363-4370 (2017). PubMed: 29067115
  • Xie Y  et al. HMGB1 regulates P-glycoprotein expression in status epilepticus rat brains via the RAGE/NF-?B signaling pathway. Mol Med Rep 16:1691-1700 (2017). PubMed: 28627626
  • Kim J  et al. Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes. Mol Med Rep 14:3655-61 (2016). PubMed: 27599553
  • Zhou Z  et al. Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NF?B Pathway Suppression. J Diabetes Res 2016:4847812 (2016). WB ; Mouse . PubMed: 27761470
  • Lin F  et al. Signaling pathways involved in the effects of HMGB1 on mesenchymal stem cell migration and osteoblastic differentiation. Int J Mol Med 37:789-97 (2016). PubMed: 26846297
  • Zhu J  et al. Advanced glycosylation end product promotes forkhead box O1 and inhibits Wnt pathway to suppress capacities of epidermal stem cells. Am J Transl Res 8:5569-5579 (2016). PubMed: 28078027
  • Jin X  et al. Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-?B Pathway. Biomed Res Int 2015:732450 (2015). Flow Cyt ; Mouse . PubMed: 26114112
  • Serratos IN  et al. Modeling the interaction between quinolinate and the receptor for advanced glycation end products (RAGE): relevance for early neuropathological processes. PLoS One 10:e0120221 (2015). PubMed: 25757085
  • Chen Y  et al. HMGB1 Contributes to the Expression of P-Glycoprotein in Mouse Epileptic Brain through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products. PLoS One 10:e0140918 (2015). WB . PubMed: 26485677
  • Yao X  et al. Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model. PLoS One 10:e0139416 (2015). IHC ; Rat . PubMed: 26448624
  • Gao S  et al. Ischemia-reperfusion injury of the retina is linked to necroptosis via the ERK1/2-RIP3 pathway. Mol Vis 20:1374-87 (2014). WB, IHC ; Rat . PubMed: 25352744
  • Yang PS  et al. Glycyrrhizin, inhibitor of high mobility group box-1, attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling in rats. Respir Res 15:148 (2014). ELISA ; Rat . PubMed: 25420924
  • Chen X  et al. RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma. Cancer Res 74:7285-97 (2014). PubMed: 25326491
  • Sessa L  et al. The receptor for advanced glycation end-products (RAGE) is only present in mammals, and belongs to a family of cell adhesion molecules (CAMs). PLoS One 9:e86903 (2014). WB ; Rat . PubMed: 24475194
  • Cheng CY  et al. Electroacupuncture-like stimulation at the Baihui (GV20) and Dazhui (GV14) acupoints protects rats against subacute-phase cerebral ischemia-reperfusion injuries by reducing S100B-mediated neurotoxicity. PLoS One 9:e91426 (2014). IHC-FoFr ; Rat . PubMed: 24626220
  • Park EY  et al. Targeting of receptor for advanced glycation end products suppresses cyst growth in polycystic kidney disease. J Biol Chem 289:9254-62 (2014). WB ; Mouse . PubMed: 24515114
  • Rodrigues T  et al. Reduction of methylglyoxal-induced glycation by pyridoxamine improves adipose tissue microvascular lesions. J Diabetes Res 2013:690650 (2013). Rat . PubMed: 23671887
  • Nunes S  et al. Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker. Cardiovasc Diabetol 12:44 (2013). WB ; Rat . PubMed: 23497124
  • Wang H  et al. S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages. Clin Cancer Res 19:3764-75 (2013). PubMed: 23719262
  • Xiao ZQ  et al. Preventive effects of polysaccharides from Liriope spicata var. prolifera on diabetic nephropathy in rats. Int J Biol Macromol 61:114-20 (2013). PubMed: 23831538
  • Crisóstomo J  et al. Methylglyoxal chronic administration promotes diabetes-like cardiac ischaemia disease in Wistar normal rats. Nutr Metab Cardiovasc Dis 23:1223-30 (2013). PubMed: 23642929
  • Shuhong Z  et al. The Effect of Dantonic Pill on ß -Catenin Expression in a Rat Model of Streptozotocin-Induced Early Stage of Diabetic Nephropathy. J Diabetes Res 2013:848679 (2013). PubMed: 23691520
  • Korngut L  et al. Overexpression of human HSP27 protects sensory neurons from diabetes. Neurobiol Dis 47:436-43 (2012). PubMed: 22569359
  • Deane R  et al. A multimodal RAGE-specific inhibitor reduces amyloid ß-mediated brain disorder in a mouse model of Alzheimer disease. J Clin Invest 122:1377-92 (2012). Mouse . PubMed: 22406537
  • Mi XS  et al. Protection of retinal ganglion cells and retinal vasculature by Lycium barbarum polysaccharides in a mouse model of acute ocular hypertension. PLoS One 7:e45469 (2012). IHC ; Mouse . PubMed: 23094016
  • Slowik A  et al. Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)--and amyloid beta 1-42-induced signal transduction in glial cells. Mol Neurodegener 7:55 (2012). IHC-P . PubMed: 23164356
  • Zhang L  et al. S100B attenuates microglia activation in gliomas: possible role of STAT3 pathway. Glia 59:486-98 (2011). Flow Cyt, IHC-Fr ; Mouse . PubMed: 21264954
  • Nguyen KD  et al. Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways. Blood 117:3793-8 (2011). PubMed: 21325601
  • Saha A  et al. Lack of an endogenous anti-inflammatory protein in mice enhances colonization of B16F10 melanoma cells in the lungs. J Biol Chem : (2010). WB ; Mouse . PubMed: 20118237
  • Takeda S  et al. From the Cover: Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A{beta} deposition in an Alzheimer mouse model with diabetes. Proc Natl Acad Sci U S A 107:7036-41 (2010). IHC-P ; Mouse . PubMed: 20231468
  • Nyeng P  et al. FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia. BMC Dev Biol 8:2 (2008). IHC-Fr ; Mouse . PubMed: 18186922
  • Ghavami S  et al. S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway. J Leukoc Biol 83:1484-92 (2008). PubMed: 18339893
  • Raucci A  et al. A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10). FASEB J : (2008). PubMed: 18603587
  • Gao X  et al. AGE/RAGE produces endothelial dysfunction in coronary arterioles in type 2 diabetic mice. Am J Physiol Heart Circ Physiol 295:H491-8 (2008). WB ; Mouse . PubMed: 18539754
  • Saha A  et al. RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis. FEBS Lett 582:3823-31 (2008). PubMed: 18948101
  • Nguyen N  et al. Diabetes mellitus accelerates cartilaginous metaplasia and calcification in atherosclerotic vessels of LDLr mutant mice. Cardiovasc Pathol 22:167-75 (0). PubMed: 22818582


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